Gene ML1954 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namecoaA
Gene length939 bp
IdentifierML1954
Location 2341570 bp
Protein summary information
Molecular mass35491.8 Da
Isoelectric point9.8
Protein length313 amino acids
Orthologs
M. tuberculosis H37RvRv1092c
M. lepromatosis Mx1-22AMLPM_1954
Cross-references
UniProtQ9X795
Gene OntologyCoenzyme a biosynthetic process, Cytoplasm, Pantothenate kinase activity, Atp binding
Enzyme Classification2.7.1.33
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable pantothenate kinase CoaA (Pantothenic acid kinase)
CommentsML1954, len: 312 aa. Probable coaA, pantothenate kinase (EC 2.7.1.33). Similar to M. tuberculosis pantothenate kinase coaA Rv1092c SW:COAA_MYCTU (O53440) (312 aa), Fasta scores: E(): 0, 93.6% identity in 312 aa overlap, and to many others e.g. Escherichia coli pantothenate kinase SW:COAA_ECOLI (P15044) (316 aa), Fasta scores: E(): 0, 53.1% identity in 311 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop).
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS23415702342508+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1954|coaA
MPRLSEPSPYVEFDRKQWRALRMSTPLALTEEELIGLRGLGEQIDLLEVEEVYLPLARLIHLQVAARQRLFAATAEFLGEPQQNPGRPVPFIIGVAGSVAVGKSTTARVLQALLARWDHHTRVDLVTTDGFLYPNAELGRRNLMHRKGFPESYNRRALMRFVTSVKSGADYACAPVYSHLRYDTIPGAKHVVRHPDILILEGLNVLQTGPTLMVSDLFDFSLYVDARIQDIEQWYVSRFLAMRGTAFADPESHFHHYSALTDSKAIIAAREIWRSINRPNLVENILPTRPRATLVLRKDADHSINRLRLRKL
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