Gene ML1987 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namectpA
Gene length2301 bp
IdentifierML1987
Location 2373434 bp
Protein summary information
Molecular mass80290.1 Da
Isoelectric point8.14
Protein length767 amino acids
Structural information
PFAMPF00122, PF00702
Orthologs
M. tuberculosis H37RvRv0092
M. lepromatosis Mx1-22AMLPM_1987
Cross-references
UniProtP46839
Gene OntologyAtp biosynthetic process, Copper-exporting atpase activity, Integral to membrane, Magnesium ion binding, Metal ion transport, Plasma membrane, Atp binding
Enzyme Classification3.6.3.-
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE CATION TRANSPORTER P-TYPE ATPASE A CTPA
CommentsML1987, len: 766 aa. Probable ctpA, cation-transporter P-type ATPase A (EC 3.6.3.-). Similar to Mycobacterium tuberculosis cation-transporting P-type ATPase A ctpA or Rv0092 or MTCY251.11 SW:CTPA_MYCTU (Q10876) (761 aa) fasta scores: E(): 0, 77.2% identity in 715 aa. Previously sequenced as SW:CTPA_MYCLE (P46839). Also similar to ML0747 and ML2000 from M. leprae. Contains multiple possible membrane spanning hydrophobic domains and Pfam match to entry PF00122 E1-E2_ATPase, E1-E2 ATPase. Contains PS00154 E1-E2 ATPases phosphorylation site.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS23734342375734+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1987|ctpA
LRAPNGWNNLPNKLSDFSTLVNSATRVAAINLSEVTQTAEVCEAVRRAALCTDGGEALQRRQADADNARYLLIRLAVAAALFVPLAHLSVMFAVLPSTHFPGWEWMLTALAIPVVTWAAWPFHRVAIHNARYHGASMETLISTGITAATIWSLYTVFGHHQSTEHRGVWRALLGSDAIYFEVAAGITVFVLAGKYYTARAKSHASIALLALAALSAKDAAVLQPDGSEMVIPANELNEQQRFVVRPGQTIAADGLVIDGSATVSMSPITGEAKPVRVNPGAQVIGGTVVLNGRLIVEAAAVGDETQLAGMVRLVEQAQQQNANAQRLADRIASVFVPCVFAVAALTAVGWLIAGSGPDRVFSAAIAVLVIACPCALGLATPTAMMVASGRGAQLGILLKGHESFEATRAVDTVVFDKTGTLTTGQLKVSAVTAAPGWQANEVLQMAATVESASEHAVALAIAASTTHREPVANFRAVPGHGVSGTVAERAVRVGKPSWIASRCNSTTLVTARRNAELRGETAVFVEIDGEQCGVIAVADAVKASAADAVAALHDRGFRTALLTGDNPASAAAVASRIGIDEVIADILPEDKVDVIEQLRDRGHVVAMVGDGINDGPALARADLGMAIGRGTDVAIGAADIILVRDNLDVVPITLDLAAATMRTIKFNMVWAFGYNIAAIPIAAAGLLNPLVAGAAMAFSSFFVVSNSLRLRNFGAILSCGTSRHRTVKRWRCPPPTRLRSTACSPVDASPLRPVAHRTGVKPPTHR
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