Gene ML1994 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namefadD10
Gene length1599 bp
IdentifierML1994
Location 2381503 bp
Protein summary information
Molecular mass56885.7 Da
Isoelectric point4.96
Protein length533 amino acids
Structural information
PFAMPF00501
Orthologues
M. tuberculosisRv0099
Cross-references
UniProtQ50176
Gene OntologyMetabolic process, Ligase activity
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)
CommentsML1994, len: 532 aa. Possible fadD10, fatty-acid-CoA synthetase (EC 6.2.1.-). Similar to Mycobacterium tuberculosis putative fatty-acid-CoA synthases e.g. Rv0099 or MTCY251.18 TR:Q10878 (EMBL:Z74410) (540 aa) fasta scores: E(): 0, 74.6% identity in 531 aa. Previously sequenced as TR:Q50176 (EMBL:Z46257). Contains Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme. Contains PS00455 Putative AMP-binding domain signature.
Functional categoryLipid metabolism
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS23815032383101+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1994|fadD10
MSHLPPTVLERILKQAHERPEAIALRRSDGTSELRYGQLVAEVNGLAAHLSAQSVSQRSRVLVISDNGPETYLSVLACAKLGAIAVMVDGNLPPATISRFSEICDPSAVLVARECRIDSSSLPEILHSIPAITVNTTADATYSACSLDIDYLAGNLNYGTDDPLAMTFTSGTTGEPKAVLLPNRTFFAIPDILREKGLAWIDWVVNETTYSPLSATHIGGLWWILNCLMHGGLCITGGEHTSSLTEVLNANKVATTCLVPTLLSKLVYELKFGDVVTPPLRLIVYGGSRVIAADVRFIEAAGVRTAQFYGLSETGCTALCLPTDNGSISKIEAGAVGRPYPGVEVYLADPNGGGPTVADTASSASFGTLWIKSPANMLGYWNNPERTREILVDGWVNTGDLVERREDGFFYIKGRSSEMIVSGGVNIVPDEVDRIAESVSGVGEAACYEIPDAHFGALVGLAVIPSAELNESTAIELKRRIAARYRRESESMARPSKIVIVADIPRTQSGKVIRATLAAALNGEQLGMVVRD
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