Gene ML2038c
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | INVOLVED IN IRON STORAGE (MAY PERFORM ANALOGOUS FUNCTIONS IN IRON DETOXIFICATION AND STORAGE AS THAT OF ANIMAL FERRITINS); FERRITIN IS AN INTRACELLULAR MOLECULE THAT STORES IRON IN A SOLUBLE, NONTOXIC, READILY AVAILABLE FORM. THE FUNCTIONAL MOLECULE, WHICH IS COMPOSED OF 24 CHAINS, IS ROUGHLY SPHERICAL AND CONTAINS A CENTRAL CAVITY IN WHICH THE POLYMERIC FERRIC IRON CORE IS DEPOSITED. |
| Product | PROBABLE BACTERIOFERRITIN BFRA |
| Comments | ML2038c, len: 159 aa. Probable bfrA, bacterioferritin. Similar to Mycobacterium tuberculosis bacterioferritin SW:BFR_MYCTU (O08465) fasta scores: E(): 0, 90.1% in 152 aa, and to Brucella melitensis bacterioferritin SW:BFR_BRUME (P49944) fasta scores: E(): 8.5e-23, 44.6% in 139 aa. Contains Pfam match to entry PF01334 Bacteriofer, Bacterioferritin. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2429330 | 2429809 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML2038c|bfrA
MQGDPDVLRLLNEQLTSELTAINQYFLHSKMQENWGFTELAERTRVESFDEMRHAEAITDRILLLDGLPNYQRIGSLRVGQTLREQFEADLAIEYEVMSRLKPGIIMCREKQDSTSAVLLEKIVADEEEHIDYLETQLALMGQLGEELYSAQCVSRPPS
Bibliography
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