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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductALANINE AND PROLINE RICH SECRETED PROTEIN APA (FIBRONECTIN ATTACHMENT PROTEIN) (Immunogenic protein MPT32) (Antigen MPT-32) (45-kDa glycoprotein) (45/47 kDa antigen)
CommentsML2055c, len: 287 aa. Probable apa (alternate gene names: mpt32, modD), Ala-, Pro-rich 45/47 kDa secreted protein. Previously sequenced Mycobacterium leprae TR:Q9R5V6 fasta scores: E(): 0, 100.0% in 287 aa. The product of this CDS has also been shown to be highly immunogenic, Mycobacterium leprae molybdate uptake protein SW:MODD_MYCLE (P46842) fasta scores: E(): 0, 99.3% in 287 aa, and highly similar to several proteins involved in the uptake of molybdenum in other mycobacteria e.g. Mycobacterium tuberculosis molybdate uptake secreted protein precursor Rv1860 SW:MODD_MYCTU (Q50906; O08062) fasta scores: E(): 0, 66.8% in 298 aa. Contains a possible N-terminal signal sequence. Previously known as modD.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS24426482443511-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML2055c|apa
MNQVDLDSTHRKGLWAILAIAVVASASAFTMPLPAAANADPAPLPPSTATAAPSPAQEIITPLPGAPVSSEAQPGDPNAPSLDPNAPYPLAVDPNAGRITNAVGGFSFVLPAGWVESEASHLDYGSVLLSKAIEQPPVLGQPTVVATDTRIVLGRLDQKLYASAEADNIKAAVRLGSDMGEFYLPYPGTRINQETIPLHANGIAGSASYYEVKFSDPNKPIGQICTSVVGSPAASTPDVGPSQRWFVVWLGTSNNPVDKGAAKELAESIRSEMAPIPASVSAPAPVG
      
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