Gene ML2061 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namendh
Gene length1401 bp
IdentifierML2061
Location 2448429 bp
Protein summary information
Molecular mass50484.8 Da
Isoelectric point9.24
Protein length467 amino acids
Structural information
PFAMPF00070, PF07992
Orthologs
M. tuberculosis H37RvRv1854c
M. lepromatosis Mx1-22AMLPM_2061
Cross-references
UniProtQ7APZ9
Gene OntologyOxidoreductase activity, Flavin adenine dinucleotide binding
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE NADH DEHYDROGENASE NDH
CommentsML2061, len: 466 aa. Probable ndh, NADH dehydrogenase (EC 1.6.99.3). Similar to Mycobacterium tuberculosis hypothetical 49.6 kda protein TR:P95160 (EMBL:Z83859) fasta scores: E(): 0, 90.2% in 460 aa, and to Corynebacterium glutamicum NADH dehydrogenase TR:Q9X710 (EMBL:AJ238250) fasta scores: E(): 0, 56.5% in 455 aa. Contains Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS24484292449829+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2061|ndh
MNAQPAATAAQDRRHQVVIIGSGFGGLNAAKKLKRANVDIKLIARTTHHLFQPLLYQVATGIISEGEIAPPTRVVLRKQRNIQVLLGNVTHIDLANQCVVSELLGHTYETLYDSLIVAAGAGQSYFGNDQFAEFAPGMKSIDDALELRGRILSAFEQAERSNDPERREKLLTFTVVGAGPTGVEMAGQIAELADHTLKGAFRRIDSTKARVVLLDAAPAVLPPMGEKLGQRAAARLQKMGVEIQLSAMVTDVDRNGITVQDSDGTVRRIESACKVWSAGVSASRLGRDLAEQSLVELDWAGRVKVLPDLSIPGYRNVFVVGDMAAIDGVPGVAQGAIQGAKYVANNIKAELGEANPAEREPFQYFDKGSMATVSRFSAVAKIGPLEFSGFIAWLMWLVLHLMYLIGFKTKITTLLSWTVTFLSTRRGQLTITEQQAFARTRLEQLAELTAESQSTAAANRATMRAS
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