Gene ML2069 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameglcB
Gene length2196 bp
IdentifierML2069
Location 2458003 bp
Protein summary information
Molecular mass80141.4 Da
Isoelectric point4.88
Protein length732 amino acids
Structural information
PFAMPF01274
Orthologs
M. tuberculosis H37RvRv1837c
M. lepromatosis Mx1-22AMLPM_2069
Cross-references
UniProtO32913
Gene OntologyGlyoxylate cycle, Malate synthase activity, Tricarboxylic acid cycle, Cytoplasm
Enzyme Classification2.3.3.9
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE MALATE SYNTHASE G GLCB
CommentsML2069, len: 731 aa. Probable glcB, malate synthase G (EC 4.1.3.2). Similar to Mycobacterium tuberculosis probable malate synthase g SW:MASZ_MYCTU (Q50596) fasta scores: E(): 0, 82.4% in 729 aa, and to Escherichia coli malate synthase g SW:MASZ_ECOLI () fasta scores: E(): 0, 56.9% in 731 aa.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS24580032460198+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2069|glcB
MTDRVSAGNLRVARVLYDFVNNEALPGTDINPNSFWSGVAKVVADLTPQNQSLLNSRDELQAQIDKWHRHRVIEPFDVDAYRQFLIDIGYLLPEPDDFTISTSGVDDEITMTAGPQLVVPVLNARFALNAANARWGSLYDALYGTDTIPETEGAEKGSEYNKIRGDKVIAYARKFMDQAVPLASDSWTNATGVSIFDGQLQIAIGTNSTGLASPEKFVGYNRQLRSSNWSVLLANHGLHIEVLIDPESPIGKTDPVGIKDVILESAITTIMDFEDSVTAVDADDKVRGYRNWLGLNKGDLTEEVNKDGKTFTRVLNADRSYTTPDGGELTLPGRSLLFVRNVGHLTTSDAILVDGGDGQEKEVFEGIIDAVFTGLAAIHGLKTGEANGPLTNSRTGSIYIVKPKMHGPAEVAFTCELFSRVEDVLGLPQGTLKVGIMDEERRTTLNLKACIKAAADRVVFINTGFLDRTGDEIHTSMEAGPMIRKGAMKNSTWIKAYEDANVDIGLAAGFKGKAQIGKGMWAMTELMADMVEQKIGQPKAGATTAWVPSPTAATLHAMHYHQVDVAAVQQELTGQRRATVDQLLTIPLAKKLAWAPEEIREEVDNDCQSILGYVVRWVDQGIGCSKVPDIHNVALMEDRATLRISSQLLANWLRHGVITSEDVRASLERMAPLVDQQNAEDPAYRPMAPNFDDSIAFLAAQELILSGAQQPNGYTEPILHRRRREFKAQNR
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