Gene ML2083c
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | Probable Acetolactate synthase IlvG (Acetohydroxy-acid synthase)(ALS) |
| Comments | ML2083c, len: 548 aa. Probable ilvG, Acetolactate synthase (EC 4.1.3.18). Similar to Mycobacterium tuberculosis probable acetolactate synthase SW:ILVG_MYCTU (Q50613) fasta scores: E(): 0, 86.1% in 548 aa, and to Bacillus subtilis acetolactate synthase large subunit SW:ILVB_BACSU (P37251; P94564) fasta scores: E(): 1.2e-32, 28.5% in 543 aa. Also similar to ML1696, ML2167 and ML0354 from M. leprae. Contains Pfam match to entry PF00205 TPP_enzymes, Thiamine pyrophosphate enzymes. Contains PS00187 Thiamine pyrophosphate enzymes signature. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2475220 | 2476866 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML2083c|ilvG
MSTDPVLTHSIHAGRLVVRRLKASGVDTVFTLSGGHLFSIYDGCRSESIRLIDTRHEQTAAFAAEGWSKVTRQPGVAVLTAGPGVTNGMSAMAAAQQNQSPLVVLGGRAPALRWGMGSLQEIDHVPFVAPLARFAATAQSADAAGRLVDEALQAAVVAPSGVGFVDFPMDYVFSMADDVGGGPGALANLPVAPAANPEALDRAAGLLAAAHRPVIMAGTNVWWGHAEAALLRLAEECQIPVLMNGMARGVVPADHPLAFSRARGKALGEADVALVVGVPMDFRLGFGKVFGSQTQLVVADRAEPDRDYPRPVAAGLYGDLPAILSALAGVGGTDSQDWIRALRTAETATRDLEKAELDDDRLPLHPMRVYAELASLLDRDAIVVIDAGDFGSYAGRVIDSYLPGCWLDSGPFGCLGSGPGYALAAKLARPNRQVVLLQGDGAFGFSGMEWDTLVRHNVPVVSVIGNNGIWGLEKHPMEALYGYSVVAELRPGTRYDEVVRALGGHGELVSVPGELRPALERAFVTGLPSVVNVLTDPSVAYPRRSNLA
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