Gene ML2118c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameechA6
Gene length744 bp
IdentifierML2118c
Location 2518777 bp
Protein summary information
Molecular mass26653.5 Da
Isoelectric point6.13
Protein length248 amino acids
Structural information
PFAMPF00378
Orthologs
M. tuberculosis H37RvRv0905
M. lepromatosis Mx1-22AMLPM_2118
Cross-references
UniProtQ50130
Gene OntologyFatty acid metabolic process, Enoyl-coa hydratase activity
Enzyme Classification4.2.1.17
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE ENOYL-CoA HYDRATASE ECHA6 (ENOYL HYDRASE) (UNSATURATED ACYL-CoA HYDRATASE) (CROTONASE)
CommentsML2118c, len: 247 aa. Possible echA6, enoyl-CoA hydratase (EC 4.2.1.17). Similar to Mycobacterium tuberculosis probable enoyl-coa hydratase echa6|Rv0905 SW:ECH6_MYCTU (Q10533) fasta scores: E(): 0, 85.8% in 247 aa, and to Escherichia coli probable enoyl-coa hydratase paaf SW:PAAF_ECOLI (P76082; P78288; O53014) fasta scores: E(): 3.1e-18, 32.1% in 252 aa. Contains Pfam match to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase family.
Functional categoryLipid metabolism
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS25187772519520-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2118c|echA6
MIGITQAEGVMTIELQRPERRNALNSQLIEKLREAVQKASSADSEVSTRVIVLTGQGTVFCAGADLSGDAFAADYPDRLIELHRVMDAVPMPVIGAINGPAIGAGLQLAMQCDLRVVAPDAYFQFPTSKYGLALDNWSIRRLSSLVGHGRARAMLLTAEKLTADIALQTGMANRIGALADAQAWAAEVTGLAPLAIQHAKRVLNDDGSIEEAWPEHKKLFDKAWTSQDVIEAQVARVEKRPPKFQGA
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