Gene ML2130c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namegltA2
Gene length1296 bp
IdentifierML2130c
Location 2531621 bp
Protein summary information
Molecular mass48079.5 Da
Isoelectric point5.18
Protein length432 amino acids
Structural information
PFAMPF00285
Orthologs
M. tuberculosis H37RvRv0896
M. lepromatosis Mx1-22AMLPM_2130
Cross-references
UniProtO33066
Gene OntologyCitrate (si)-synthase activity, Cytoplasm, Cellular carbohydrate metabolic process
Enzyme Classification2.3.3.1
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE CITRATE SYNTHASE I GLTA2
CommentsML2130c, len: 431 aa. Probable gltA2, citrate synthase 1 (EC 4.1.3.7). Similar to Mycobacterium tuberculosis citrate synthase 1 Rv0896 SW:CISY_MYCTU (Q10530) fasta scores: E(): 0, 91.0% in 431 aa, and to Corynebacterium glutamicum citrate synthase SW:CISY_CORGL (P42457) fasta scores: E(): 0, 62.7% in 432 aa. Contains Pfam match to entry PF00285 citrate_synt, Citrate synthase. Contains PS00480 Citrate synthase signature.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS25316212532916-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2130c|gltA2
VADTDDTVTLKYPGGEIDLQIVRATEGNDGIAIVPVLAKTGYTTFDVGYGNTASTKSSITYIDGDAGILRYRGYPIEQLAEKSTFIEVCYLLIYGELPATDQLAEFTHRIQRHTMLHEDLKRFYDGFPRNAHPMPVLSSVVNALSAYYQDALDPMDNGQVELSTIRLLAKLPTIAAYAYKKSVGQPFLYPDNAFSLVENFLRMTFGLPAEPYEPDPEVVRALDMLFILHADHEQNCSTSTVRLVGSSRANLFTSISGGINALWGPLHGGANQAVLEMLEGIRESGDDVGGFVQKVKNCQAGVKLMGFGHRVYKNYDPRARIVKEQADKILVKLGGDDDLLNIAKGLEEAALTDDYFIERKLYPNVDFYTGLIYRALGFPTRMFTVLFALGRLPGWIAHWREMHDEGDSKIGRPRQIYTGYTERDYTAIETR
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