Gene ML2143 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML2143
Gene length1740 bp
IdentifierML2143
Location 2543933 bp
Protein summary information
Molecular mass61674.6 Da
Isoelectric point11.13
Protein length580 amino acids
Orthologs
M. tuberculosis H37RvRv0876c
M. lepromatosis Mx1-22AMLPM_2143
Cross-references
UniProtO33057
Gene OntologyPlasma membrane, Integral to membrane
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE CONSERVED TRANSMEMBRANE PROTEIN
CommentsML2143, len: 579 aa. Possible conserved transmembrane protein. Similar to Mycobacterium tuberculosis hypothetical 57.9 kda protein Rv0876c SW:Y876_MYCTU (Q10564) fasta scores: E(): 0, 81.2% in 568 aa, and to Streptomyces coelicolor putative integral membrane protein TR:CAB93403 (EMBL:AL357524) fasta scores: E(): 5.3e-16, 38.8% in 448 aa. Contains possible membrane spanning hydrophobic domains.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS25439332545672+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2143|ML2143
VSGRRRNHPGRLASIPGLRTRTGSRNQHPGIANYPADSSDFRPAQQRRALEQREQQAGQLDPARRSPSMPSANRYLPPLGQQQSEPQHNSAPPCGPYPGERIKVTRAAAQRSREMGYRMYWMVQRAATADGADKSGLTALTWPVVTNFAVDSAMAVALANTLFFAAASGESKSKVALYLLITIAPFAVIAPLIGPALDRLQHGRRVALATSFVLRTGLATLLIMNYDGATGSYPSMVLYPCALAMMVLSKSFSVLRSAVTPRVMPPSIDLVRVNSRLTVFGLLGGTIAGGAIAAGVEFVCAHLFKLPGALFVVAAITISGALLSMRIPRWVEVTAGEIPATLSYRLHRKPLRQSWPEEVKKVSGRLRQPLGRNIITSLWGNCTIKVMVGFLFLYPAFVAKEHQANGWVQLGMLGLIGTAAAIGNFAGNFTSARLQLGRPAVLVVRCTIAVTVLALAASVAGNLLMTTIATLITSGSSAIAKASLDASLQNDLPEESRASGFGRSESTLQLAWVLGGALGVMVYTDLWVGFTAVSALLILGLAQTVVSFRGDSLIPGLGGNRPVMIEQESMRRAAAVSPQ
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