Gene ML2157 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameercC3
Gene length1650 bp
IdentifierML2157
Location 2559343 bp
Protein summary information
Molecular mass60877.2 Da
Isoelectric point6.57
Protein length550 amino acids
Structural information
PFAMPF00271, PF04851
Orthologues
M. tuberculosisRv0861c
Cross-references
UniProtQ9CBE0
Gene OntologyAtp-dependent dna helicase activity, Dna binding, Nucleotide-excision repair, Atp binding
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE DNA HELICASE ERCC3
CommentsML2157, len: 549 aa. Probable ercC3, DNA helicase (EC 3.6.1.-). Similar to Mycobacterium tuberculosis putative DNA helicase Rv0861c|TR:O53873 (EMBL:AL022004) fasta scores: E(): 0, 91.1% in 542 aa, and to Saccharomyces cerevisiae DNA repair helicase RAD25 SW:RA25_YEAST (Q00578) fasta scores: E(): 0, 29.3% in 611 aa. Contains Pfam match to entry PF00271 helicase_C, Helicases conserved C-terminal domain.
Functional categoryInformation pathways
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS25593432560992+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2157|ercC3
MTDGPLIVQSDKTVLLEVNHKLADAARAAIAPFAELERAPEHVHTYRITPLALWNARAAGHDAEQVVDTLISHARYAVPQPLLVDIVDTMARYGRLQLVKNPAHGLTLVSLDRTVLEEVLHNKKIAPMVGGRIDDDTVVVHPSERGRIKQLLLKIGWPAEDLAGYVDGEAHPIILHQDGWQLRDYQRLAADSFWSGGSGVVVLPCGAGKTLVGAAAMAKTGATTLILVTNIVVARQWKRELITHTSLTEDEIGEYSGERKEIRPVTISTYQMITHRTKGEYRHLELFNSRDWGLIIYDEVHLLPAPVFRMTADLQSKRRLGLTATLIREDGREGDVFSLIGPKRYDTPWKDLEEQGWIAPAKCVEVRVTLTNNERMTYATAEPEERYRVCSTAHSKIAVVKSVLSRHPGEQTLVIGAYLDQLNELGSELNAPIIQGSTRTKEREALFDAFRRGEVFTLVVSKVANFSIDLPEAAVAVQVSGTFGSRQEEAQRLGRLLRPKADGGGAIFYSVVARDSLDAEYAAHRQRFLAEQGYSYIIRDADDLLGPAI
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