Gene ML2189c in Mycobacterium leprae TN
Go to browser
virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namephoT
Gene length777 bp
IdentifierML2189c
Location 2604280 bp
Protein summary information
Molecular mass28248.3 Da
Isoelectric point5.01
Protein length259 amino acids
Structural information
PFAMPF00005
Orthologs
M. tuberculosis H37RvRv0820
M. lepromatosis Mx1-22AMLPM_2189
Cross-references
UniProtQ50046
Gene OntologyInorganic phosphate transmembrane transporter activity, Phosphate ion transmembrane-transporting atpase activity, Phosphate ion transport, Plasma membrane, Atp binding
Enzyme Classification3.6.3.27
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE PHOSPHATE-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER PHOT
CommentsML2189c, len: 258 aa. Probable phoT, phosphate-transport ATP-binding protein ABC transporter. Similar to Mycobacterium tuberculosis phosphate transport system ATP-binding protein TR:O53832 (EMBL:AL022004) fasta scores: E(): 0, 91.5% in 258 aa, and to Escherichia coli phosphate transport ATP-binding protein pstb SW:PSTB_ECOLI (P07655) fasta scores: E(): 0, 52.9% in 255 aa. Also similar to ML1892, ML1114, ML1113, ML1122, ML1089, ML1424, ML0336, ML2352, ML1726, ML0669, ML0590 and ML1816 from M. leprae. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00211 ABC transporters family signature.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS26042802605056-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2189c|phoT
VAKRLDLKGVNIYYGSFQAVLDVSLAVLPRSVTAFIGASGCGKTTVLRTLNRMHEVVPGARVEGTVLLDDEDIYAPGIDPVGVRRAIGMVFQRPNPFPAMSIRDNVVAGLKLQGVRNRKVLDDTAEYFLRGTNLWDEVKDRLDKPGGGLSGGQQQRLCIARAIAVQPDVLLMDEPCSSLDPISTMAIEELIGELKQEYTIVIVTHNMQQAARVSDQTAFFNLEAVGRPGRLVEIDDTEKIFSNPTEKATEDYISGRFG
Bibliography
No article yet recorded