Gene ML2196 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namethiX
Gene length423 bp
IdentifierML2196
Location 2610916 bp
Protein summary information
Molecular mass15155.3 Da
Isoelectric point6.92
Protein length141 amino acids
Structural information
PFAMPF00085
Orthologs
M. tuberculosis H37RvRv0816c
M. lepromatosis Mx1-22AMLPM_2196
Cross-references
UniProtQ9CBC8
Gene OntologyCell redox homeostasis
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE THIOREDOXIN THIX
CommentsML2196, len: 140 aa. Probable thiX, thiredoxin. Similar to Mycobacterium tuberculosis putative thioredoxin Rv0816c TR:O53828 (EMBL:AL022004) fasta scores: E(): 1.1e-30, 63.8% in 141 aa, and to Anacystis nidulans thioredoxin 1 SW:THI1_ANANI (P12243) fasta scores: E(): 9e-07, 37.6% in 93 aa. Also similar to ML2703 from M. leprae. Contains PS00194 Thioredoxin family active site.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS26109162611338+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2196|thiX
MMTAIVATITVGMLTAFTGRWLTRHSGNVHEICSGPGQGTGTDTADLGLSRTGPTIVHFSAPWCGPCDRVRRVVYQVCKDLPDVAHIEIDLDTNPAAVRRFSVLSLPTTLIFDTDGQQRYRTSGVPKAFDLLSTLEPLLA
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