Gene ML2213c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namepepC
Gene length1332 bp
IdentifierML2213c
Location 2630076 bp
Protein summary information
Molecular mass47272.7 Da
Isoelectric point6.41
Protein length444 amino acids
Structural information
PFAMPF02127
Orthologs
M. tuberculosis H37RvRv0800
M. lepromatosis Mx1-22AMLPM_2213
Cross-references
UniProtQ50022
Gene OntologyMetallopeptidase activity, Proteolysis, Vacuole, Zinc ion binding, Aminopeptidase activity
Enzyme Classification3.4.11.-
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE AMINOPEPTIDASE PEPC
CommentsML2213c, len: 443 aa. Probable pepC, aminopeptidase I (EC 3.4.11.-). Similar to Mycobacterium tuberculosis aminopeptidase Rv0800 OR MTCY07H7A.09C TR:O06634 (EMBL:Z95618) fasta scores: E(): 0, 78.3% identity in 433 aa, and to Saccharomyces cerevisiae vacuolar aminopeptidase I precursor ApE1 SW:AMPL_YEAST (P14904; P22060) fasta scores: E(): 5.7e-22, 31.5% identity in 454 aa. Contains Pfam match to entry PF02127 Peptidase_M18, Aminopeptidase I zinc metalloprotease (M18).
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS26300762631407-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2213c|pepC
MPTLASTTSSPTAMMLGMPASAADLCEFINASPSPFHVCATVAGRLLDAGYAELSEVERWPDHPGRYFIVRAGSLVAWSAGQGVKAHAPFRIVGAHTDSPNLRVKQHPDLLVAGWRVVALQPYGGAWLNSWLDRDLGVSGRLSVRSAGKGSEITDRLVRIDDPILRVPQLAIHLAEDRKSLTLDPQRHVNAVWGVGDKAGSLLEYVAERTGVAVADVLAVDLMTHDLVPSMVIGADANLLSAPRLDNQVSCYAGMEALLASVPHDCLPVLALFDHEEVGSTSDRGARSNLLSTVLERIVLAAGGGRDDYLRRLPASLLVSADMAHATHPNYPECHEPSHLIEVNAGPVLKVHPNLRYATDGRTAAAFEVACQQAGVRLQRYEHRADRPCGSTIGPLASARTGIPTVDVGAAQLAMHSARELMGAHDVAVYSAALQAFFSADLF
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