Gene ML2263c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namemenB
Gene length903 bp
IdentifierML2263c
Location 2686566 bp
Protein summary information
Molecular mass33308.5 Da
Isoelectric point7.34
Protein length301 amino acids
Structural information
PFAMPF00378
Orthologs
M. tuberculosis H37RvRv0548c
M. lepromatosis Mx1-22AMLPM_2263
Cross-references
UniProtQ9CBB5
Gene Ontology1,4-dihydroxy-2-naphthoyl-coa synthase activity, Menaquinone biosynthetic process
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE NAPHTHOATE SYNTHASE MENB (DIHYDROXYNAPHTHOIC ACID SYNTHETASE) (DHNA SYNTHETASE)
CommentsML2263c, len: 300 aa. Probable menB, naphthoate synthase (EC 4.1.3.36). Similar to Mycobacterium tuberculosis MenB or Rv0548c or MTCY25D10.27C TR:O06414 (EMBL:Z95558) fasta scores: E(): 0, 91.9% identity in 308 aa, and to Bacillus subtilis naphthoate synthase MENB SW:MENB_BACSU (P23966) fasta scores: E(): 0, 50.4% identity in 270 aa. Contains Pfam match to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase family.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS26865662687468-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2263c|menB
LSNNPFDAKLWRLIDGFGDLTDITYHRYVNGATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPSPRDGVWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVICDLTLASREHARFKQTDADVGSFDGGYGSAYLARQIGQKFAREIFLLGRAYTAEQMHHMGAVNAVAEHANLETMGLEWAAEINAKSPQAQRMLKFAFNLLDDGLVGQQLFAGEATRLAYMTDEAVEGRDAFLQKRAPDWSSFPRYF
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