Gene ML2276c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML2276c
Gene length1227 bp
IdentifierML2276c
Location 2698914 bp
Protein summary information
Molecular mass43853.9 Da
Isoelectric point9.37
Protein length409 amino acids
Structural information
PFAMPF01266, PF07992
Orthologs
M. tuberculosis H37RvRv0561c
M. lepromatosis Mx1-22AMLPM_2276
Cross-references
UniProtQ9CBA6
Gene OntologyOxidoreductase activity, Metabolic process
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
Productpossibleputative FAD-linked oxidoreductase
CommentsML2276c, len: 408 aa. Possible FAD-linked oxidoreductase. Similar to Mycobacterium tuberculosis putative oxidoreductase Rv0561c or MTCY25D10.40C TR:O06427 (EMBL:Z95558) (408 aa) fasta scores: E(): 0, 84.5% identity in 406 aa. Shows weak similarity to many oxidoreductases e.g. Escherichia coli FixC protein fixC SW:FIXC_ECOLI (P31575; P75626) (428 aa) fasta scores: E(): 1.7e-05, 25.4% identity in 417 aa. Contains Pfam match to entry PF01494 FAD_binding_3, FAD binding domain.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS26989142700140-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2276c|ML2276c
VRVETSADVVVVGAGPAGSAAATWAARAGNDVIVIDSVCFPRDKACGDGLTPRAVAELKRLGLDDWLNTRIRHRGLRMSGFGGEVEVDWPGPSFPSTSSAVPRLELDDRIRKVAENSGARMLLGTKAVSVYHDSSRRAASVTLADGTEVGCRQLIIADGARSPLGRKLGRSWHQKTVYGVAARGYLTTPRSDDLWLTSHLELRSPDGAVLPGYGWIFPLGNGEVNIGVGALSTSKRPADLALRSLISYYTDLRRHEWGFSGQPRAVSSALLPMGGAVSGVAGPNWMLIGDAAACVNPLNGEGIDYGLETGRLAAELLDLRDLSYVWPSLLQQHYGRGFSVARRLALLLTFKRCLPAIGPSAMRSTSLITIAVRVMANLVTDDDADWVARVWRSGGWASWLVDRRPPFS
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