Gene ML2277
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE POLYPRENYL-DIPHOSPHATE SYNTHASE GRCC1 (POLYPRENYL PYROPHOSPHATE SYNTHETASE) |
| Comments | ML2277, len: 330 aa. Probable grcC1, polyprenyl diphosphate synthase (EC 2.5.1.-). Similar to Mycobacterium tuberculosis polyprenyl diphosphate synthase Rv0562 or MTCY25D10.41 TR:O06428 (EMBL:Z95558) (335 aa) fasta scores: E(): 0, 76.4% identity in 335 aa and to Mycobacterium tuberculosis isoprene biosynthesis transferase Rv0989c or MTCI237.03C TR:O05572 (EMBL:Z94752) (325 aa) fasta scores: E(): 0, 53.6% identity in 323 aa. Similar to many polyprenyl synthase components e.g. Bacillus stearothermophilus heptaprenyl diphosphate synthase component ii hepT or heps-2 SW:HEP2_BACST (P55785) (320 aa) fasta scores: E(): 1.2e-31, 33.8% id in 320 aa. Contains Pfam match to entry PF00348 polyprenyl_synt, Polyprenyl synthetases. Contains PS00444 Polyprenyl synthetases signature 2. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2700171 | 2701163 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML2277|grcC1
MVVAGINFGDAAFAATVQDRVVRIEQLMDAELRDTDEVMTESVLHLFAAGGKRFRPLFTVLSAQIGPRPDAPEVIIAGAVIELVHLASLYHDDVMDEAEVRRGAPSANLRWSNSVAILAGDYLFATASRLVSQLGLDAVRIIADTFAQLVTGQMRETRGVPEGADSIEQYLKVVYEKTGCLIGSAGRLGGLFAGAHAEQVERLSRLGSIVGTAFQISDDIIDIDSDYTKSGKLPGTDVREGVRTLPILYALRETGPDSERLRALLAGPVDNDAEVVEALALLRASPGMARARQVLAHYADQASGELAQLPDGPSRDALATLVDYTTNRHG
Bibliography
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