Go to browser
virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE POLYPRENYL-DIPHOSPHATE SYNTHASE GRCC1 (POLYPRENYL PYROPHOSPHATE SYNTHETASE)
CommentsML2277, len: 330 aa. Probable grcC1, polyprenyl diphosphate synthase (EC 2.5.1.-). Similar to Mycobacterium tuberculosis polyprenyl diphosphate synthase Rv0562 or MTCY25D10.41 TR:O06428 (EMBL:Z95558) (335 aa) fasta scores: E(): 0, 76.4% identity in 335 aa and to Mycobacterium tuberculosis isoprene biosynthesis transferase Rv0989c or MTCI237.03C TR:O05572 (EMBL:Z94752) (325 aa) fasta scores: E(): 0, 53.6% identity in 323 aa. Similar to many polyprenyl synthase components e.g. Bacillus stearothermophilus heptaprenyl diphosphate synthase component ii hepT or heps-2 SW:HEP2_BACST (P55785) (320 aa) fasta scores: E(): 1.2e-31, 33.8% id in 320 aa. Contains Pfam match to entry PF00348 polyprenyl_synt, Polyprenyl synthetases. Contains PS00444 Polyprenyl synthetases signature 2.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS27001712701163+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML2277|grcC1
MVVAGINFGDAAFAATVQDRVVRIEQLMDAELRDTDEVMTESVLHLFAAGGKRFRPLFTVLSAQIGPRPDAPEVIIAGAVIELVHLASLYHDDVMDEAEVRRGAPSANLRWSNSVAILAGDYLFATASRLVSQLGLDAVRIIADTFAQLVTGQMRETRGVPEGADSIEQYLKVVYEKTGCLIGSAGRLGGLFAGAHAEQVERLSRLGSIVGTAFQISDDIIDIDSDYTKSGKLPGTDVREGVRTLPILYALRETGPDSERLRALLAGPVDNDAEVVEALALLRASPGMARARQVLAHYADQASGELAQLPDGPSRDALATLVDYTTNRHG
      
Bibliography
No article yet recorded