Gene ML2278
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE PROTEASE TRANSMEMBRANE PROTEIN HEAT SHOCK PROTEIN HTPX |
| Comments | ML2278, len: 287 aa. Probable htpX, protease heat shock protein X (EC 3.4.24.-) (transmembrane protein). Similar to Mycobacterium tuberculosis probable protease htpX or Rv0563 or MTV039.01 or MTCY25D10.42 SW:HTPX_MYCTU (O06429) (286 aa) fasta scores: E(): 0, 88.5% identity in 286 aa. Similar to many homologues of Escherichia coli probable protease and heat-shock protein HtpX SW:HTPX_ECOLI (P23894) (293 aa) blastp scores: 78.1 bits, 30% identity in 253 aa. Contains hydrophobic, possible membrane-spanning regions. Contains Pfam match to entry PF01435 Peptidase_M48, Peptidase family M48. Contains PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. |
| Functional category | Virulence, detoxification, adaptation |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2701274 | 2702137 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML2278|htpX
MTWHPQANRLKTFVLLVGMSTLIVVVGAIFGRTALFFATLVAVGINVYTYYNSDKLALRAMHAQPVSEVQAPVMYRIVRELATGAHQPMPRLYISDTNAPNAFATGRNPRNAAVCCTTGILEILNERELRAVLGHELSHVYNRDILISCVAGALAGVITALANMAMWAGTFGTTRDEENPFALLLVSLLGPIAATVVRLAVSRSREYQADESGAMLTGDPLALASALRKISSGVQAAPLPPEPQLASQAHLMIANPFRVGDRIGSLFSTHPPIEDRIRRLETMVAGR
Bibliography
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