Gene ML2295c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML2295c
Gene length705 bp
IdentifierML2295c
Location 2720563 bp
Protein summary information
Molecular mass23835.6 Da
Isoelectric point6.88
Protein length235 amino acids
Orthologs
M. tuberculosis H37RvRv3668c
M. lepromatosis Mx1-22AMLPM_2295
Cross-references
UniProtQ9CB98
Gene OntologyCatalytic activity
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE PROTEASE
CommentsML2295c, len: 234 aa. Possible protease (EC 3.4.-.-). Similar to Mycobacterium tuberculosis possible protease Rv3668c or MTV025.016C TR:O69636 (EMBL:AL022121) (232 aa) fasta scores: E(): 0, 77.1% identity in 231 aa. Shows weak similarity to the C-terminal half of some proteases e.g. Thermomonospora fusca alkaline serine protease precursor TR:O86984 (EMBL:U65895) (368 aa) fasta scores: E(): 0.0018, 31.4% identity in 153 aa.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS27205632721267-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2295c|ML2295c
LVLRRGHWCILVALVAVLLAVVSMPAKTVFADGRLPMGGGAGIVINGDTMCTLTTIGTDSAAELIGFTSAHCGGPGAQVAAEGAENRGPMGTMIAGNDNLDYAVIKFDPAKVMPVAAYNGFVISGIGQDPAFGQIACKQGRTTGNSCGVAWGMGETSGTLVMQVCGRPGDSGAPVTVNNLLVGMIHGAFTDNLPVCITKFIPLHTPAVVMSMNAILADVNKNNRPGAGFVPQPV
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