Gene ML2302
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY CRP/FNR-FAMILY) |
| Comments | ML2302, len: 224 aa. Probable transcriptional regulatory protein (Crp/Fnr family). Similar to Mycobacterium tuberculosis putative transcriptional regulator Rv3676 or MTV025.024 TR:O69644 (EMBL:AL022121) (224 aa) fasta scores: E(): 0, 96.0% identity in 224 aa. Similar to many e.g. Haemophilus influenzae catabolite gene activator crp or cap or HI0957 SW:CRP_HAEIN (P29281) (224 aa) fasta scores: E(): 2.4e-14, 32.6% identity in 187 aa. Also similar to ML2345 a possible pseudogene similar to M. tuberculosis Rv3676. Contains a probable helix-turn-helix motif at aa 175-196 (Score 1990, SD +5.96) Contains Pfam match to entry PF00325 crp, Bacterial regulatory proteins, crp family. Contains Pfam match to entry PF00027 cNMP_binding, Cyclic nucleotide-binding domain. |
| Functional category | Regulatory proteins |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2726917 | 2727591 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML2302|ML2302
VDEILARAGIFQGVEPSAVAALTKQLQPVDFPRGHTVFTEGEPGDRLYIIVSGKVKIGRRSPDGRENLLTIMGPSDMFGELSIFDPGPRTSSATTITEVRAVSMDRDALRAWIADRPEIAEQLLRVLARRLRRTNNNLADLIFTDVPGRVAKQLLQLAQRFGTQEGGAMRVTHDLTQEEIAQLVGASRETVNKALADFAHRGWIRLDGKSVLISDSERLARRAR
Bibliography
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