Gene ML2327 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namecobQ2
Gene length693 bp
IdentifierML2327
Location 2758991 bp
Protein summary information
Molecular mass24442.0 Da
Isoelectric point5.64
Protein length231 amino acids
Structural information
PFAMPF07685
Orthologs
M. tuberculosis H37RvRv3713
M. lepromatosis Mx1-22AMLPM_2327
Cross-references
UniProtQ7APW5
Gene OntologyCobalamin biosynthetic process, Glutamine metabolic process, Catalytic activity
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE COBYRIC ACID SYNTHASE COBQ2
CommentsML2327, len: 230 aa. Possible cobQ2, cobyric acid synthase. Similar to Mycobacterium tuberculosis cobQ2, cobyric acid synthase Rv3713 TR:O69680 (EMBL:AL022121) (231 aa) fasta scores: E(): 0, 86.5% identity in 230 aa. Also weakly similar to others e.g. Pseudomonas denitrificans cobB SW:COBB_PSEDE (P21632) (433 aa) fasta scores: E(): 0.0027, 30.7% identity in 166 aa. Contains Pfam match to entry PF01656 CBIA, Cobyrinic acid a,c-diamide synthase.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS27589912759683+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2327|cobQ2
VRIGLVLPDVMGTYGDGGNAVVLRQRLLLRGIAAEIVELTLADPVPESLDLYTLGGAEDYAQRLATRHLLRYPGLQHAASYGAPVLAICAAVQVLGQWYETASRERVDGVGLLDVTTAPQDVRTIGELVSTPLLTSLNQRLSGFENHRGGTVLGPAATPLGAVVKGAGNRVGDHFDGVIQGSVMATYMHGPCLARNPELADLLLSKVVGELAPLELPEVELLRRERLAAR
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