Gene ML2391c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namemca
Gene length873 bp
IdentifierML2391c
Location 2861609 bp
Protein summary information
Molecular mass32542.5 Da
Isoelectric point5.95
Protein length291 amino acids
Structural information
PFAMPF02585
Orthologs
M. tuberculosis H37RvRv1082
M. lepromatosis Mx1-22AMLPM_2391
Cross-references
UniProtQ7APV3
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductMycothiol conjugate amidase Mca (Mycothiol S-conjugate amidase)
CommentsML2391c, len: 290 aa. Probable mca, mycothiol conjugate amidase. Similar to Mycobacterium tuberculosis mca, mycothiol conjugate amidase Rv1082 TR:O53430 (EMBL:AL021897) (288 aa) fasta scores: E(): 0, 86.4% identity in 287 aa. Also weakly similar to Streptomyces lincolnensis lmbE TR:Q54358 (EMBL:X79146) (270 aa) fasta scores: E(): 8.9e-13, 33.0% identity in 282 aa. Also similar to ML1495 from M. leprae.
Functional categoryVirulence, detoxification, adaptation
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS28616092862481-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2391c|mca
VSELRLMAVHAHPDDESSKGAATLARYADEGHRVLVVTLTGGERGEILNPAMDLPDVHGHIAEIRRDEMAKAAEILGVEHTWLGFIDSGLPKGDPPPPLPDDCFALVPLEVCTEALVRVVRKFRPHVLTTYDENGGYPHPDHIRCHQVSVDAYEAACDYRRFPDAGKPWTVSKLYYNHGFLRARMQLLHDEFAKHGQAGPFDKWLAQSNPAHDPFESRVTTRVECSAYFSQRDDALRAHATQIDPKAEFFAAPISWQQRLWPTEEFELARSRVPTRLPEHDLFAGIEAAG
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