Gene ML2401 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameechA9
Gene length1038 bp
IdentifierML2401
Location 2871776 bp
Protein summary information
Molecular mass36594.2 Da
Isoelectric point4.52
Protein length346 amino acids
Structural information
PFAMPF00378
Orthologs
M. tuberculosis H37RvRv1071c
M. lepromatosis Mx1-22AMLPM_2401
Cross-references
UniProtQ7APV2
Gene OntologyMetabolic process, Isomerase activity
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE ENOYL-CoA HYDRATASE ECHA9 (ENOYL HYDRASE) (UNSATURATED ACYL-CoA HYDRATASE) (CROTONASE)
CommentsML2401, len: 345 aa. Possible echA9, enoyl-CoA hydratase (EC 4.2.1.17). Similar to several putative Prokaryotic and Eukaryotic enoyl-CoA hydratases including: Mycobacterium tuberculosis Rv1071c TR:O53419 (EMBL:AL021897) (345 aa) fasta scores: E(): 0, 77.7% id in 345 aa and Arabidopsis thaliana putative 3-hydroxyisobutyryl-coenzyme A hydrolase TR:O49330 (EMBL:AC002340) (410 aa) fasta scores: E(): 0, 35.1% id in 345 aa. Contains Pfam match to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase family.
Functional categoryLipid metabolism
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS28717762872813+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2401|echA9
VAGESDEVLARVEAGIGLITLNRPKAINSLNQQMVDALTAILTSWADDDAVRAVVLSGAGERGLCAGGDVVAIYHSALKDGVEARRFWRSEYLLNSQIARFPKPYVSLMDGIVMGGGVGIGAHANTRVVTDTSQVAMPEVGIGFIPDVGGTYLLSRAPGALGLHVALTGAPFSGADAIELGFADHYVPHSDLNAFTRAVVTDGVNSALAGYAIEPPPSYLAAQRDWIDECYVGETVKDIITALRGHDAEPAEGAFNLIVSRSPVALSVTLEAMRRAAKLETLTDVLTQDYRVSSASLHSHDLVEGIRAQLVHKDRNPQWAPTTLAEVTAADICGYFEPVDDDLSF
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