Gene ML2420c
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE UROPORPHYRIN-III C-METHYLTRANSFERASE HEMD (UROPORPHYRINOGEN III METHYLASE) (UROGEN III METHYLASE) (SUMT) (UROGEN III METHYLASE) (UROM) |
| Comments | ML2420c, len: 563 aa. Probable hemD, uroporphyrin-III C-methyltransferase (EC 2.1.1.107). Similar to Mycobacterium tuberculosis Rv0511 TR:P95077 (EMBL:Z83865) (565 aa) fasta scores: E(): 0, 85.7% identity in 565 aa and to Clostridium josui porphyrin biosynthesis protein HemD [includes: uroporphyrin-III C-methyltransferase hemD SW:HEM4_CLOJO (Q59294) (504 aa) fasta scores: E(): 3e-24, 24.4% identity in 545 aa. Contains Pfam match to entry PF00590 TP_methylase, Tetrapyrrole (Corrin/Porphyrin) Methylases. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2894843 | 2896534 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML2420c|hemD
VVGATMTTRGRKLRPGRITFVGAGPGAPGLLTAQAVAVLANAALVFIDPDVPEPVLALIGKDLPPVSGPAPAGPAAVTAGRAADGTLEGDHYQAAPMVMSGGADIRPALGDPTEVAKTLTAEARSGVDVVRLVAGDPLTVDAVIAEVNAVARTNLQIEIVPGLVTSSVVPTYAGLPLGSSHTVADVRGDVDWEALAAAPGPLILQATASHLADAAHILIDHGLDDATPCVVTAQGTTCQQRSVETTLEGLADSAVLVGTDTAGPLTGPLVVTIGKTVTSRARLNWWESRALYGWTVLVPRTKDQAGEMSERLTSYGALPVEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFTSTNAVRAVWEKFGEFGLDARAFSGVKIACVGEATADRVRAFGISPELVPAGEQSSLGLLDEFPPYDSVFDPVNRVLLPRADIATETLAEGLRGCGWEIEDVTAYRTVRAAPPPAATREMIKTGGFDAVCFTSSSTVRNLVGIAGKPHARTVIACIGPKTAETASEFGLRVDVQPETAAVGPLVDALAEHVARLRAEGALPPPRKKSRRR
Bibliography
No article yet recorded
