Gene ML2441c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namegpm1
Gene length744 bp
IdentifierML2441c
Location 2916624 bp
Protein summary information
Molecular mass27481.0 Da
Isoelectric point5.36
Protein length248 amino acids
Structural information
PFAMPF00300
Orthologs
M. tuberculosis H37RvRv0489
M. lepromatosis Mx1-22AMLPM_2441
Cross-references
UniProtP53531
Gene OntologyGlycolysis, 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity
Enzyme Classification5.4.2.1
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE PHOSPHOGLYCERATE MUTASE 1 GPM1 (PHOSPHOGLYCEROMUTASE) (PGAM) (BPG-DEPENDENT PGAM)
CommentsML2441c, len: 247 aa. Probable gpm1, phosphoglycerate mutase. Highly similar to many phosphoglycerate mutases including: Streptomyces coelicolor SW:PMGY_STRCO (P33158) (252 aa) fasta scores: E(): 0, 66.3% identity in 240 aa, and Mycobacterium tuberculosis phosphoglycerate mutase Rv0489 SW:PMGY_MYCTU (Q11140) (249 aa) fasta scores: E(): 0, 89.0% identity in 236 aa. Contains Pfam match to entry PF00300 PGAM, Phosphoglycerate mutase family.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS29166242917367-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2441c|gpm1
MQQGNTATLILLRHGESDWNARNLFTGWVDVGLTDKGRAEAVRSGELLAEHNLLPDVLYTSLLRRAITTAHLALDTADWLWIPVRRSWRLNERHYGALQGLDKAVTKARYGEERFMAWRRSYDTPPPPIEKGSEFSQDADPRYTDIGGGPLTECLADVVTRFLPYFTDVIVPDLRTGRTVLIVAHGNSLRALVKHLDEMSDDEVVGLNVPTGIPLRYDLDADLRPVVPGGTYLDPEAAAAVISQARP
Bibliography
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