Gene ML2446c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namelprQ
Gene length1326 bp
IdentifierML2446c
Location 2921391 bp
Protein summary information
Molecular mass46863.4 Da
Isoelectric point5.91
Protein length442 amino acids
Structural information
PFAMPF03734
Orthologs
M. tuberculosis H37RvRv0483
M. lepromatosis Mx1-22AMLPM_2446
Cross-references
UniProtQ9CB49
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE CONSERVED LIPOPROTEIN LPRQ
CommentsML2446c, len: 441 aa. Probable lprQ, conserved lipoprotein. Similar to Mycobacterium tuberculosis lipoprotein lprQ Rv0483 SW:Y483_MYCTU (Q11149) fasta scores: E(): 0, 79.3% identity in 439 aa, and to Streptomyces coelicolor putative lipoprotein TR:CAB76012 (EMBL:AL157916) fasta scores: E(): 2.5e-24, 28.6% identity in 405 aa. Also similar to ML0426 from M. leprae. Contains a possible N-terminal signal sequence and an appropriately positioned Prokaryotic membrane lipoprotein lipid attachment site. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS29213912922716-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2446c|lprQ
VIASTPRQNRESINRRVALTALGVGVFAPSVFVACAGSAIKPSEKKTTPAPHLTFQPATATDDVIPVAPISVQIADGWFQRVTLTNPVGKVVAGVFNQDRTVYTITEPLGYDTTYTWNGSAVGHDGKAVPVTGKFSTVTPVKKVNGGFQLADGQTVGVAAPIIIQFDAPISDKSAVEKALTVTTTPPVEGSWAWLPDEAKGARIHYRPREYYPAGTTVNVDAKLYGLPFGDGAYGLQDMSLNIQIGRRQVVKAEVSSHRIQVVTDAGVIMDFPCSYGEADQARNVTRNGIHVVTEKYSDFYMSNPAAGYSNVYERWAVRISNNGEFIHANPASVGAQGNTNVTNGCINLSTGDAEQFYRSAIYGDPVEVTGSSIQLSYSDGDIWDWAVDWDTWVGMSALLSFPTVHQPATQIPVTAPVTPPGAPILSGTPTSGSGTARPGG
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