Gene ML2451c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namedeoC
Gene length681 bp
IdentifierML2451c
Location 2926564 bp
Protein summary information
Molecular mass22494.7 Da
Isoelectric point4.86
Protein length227 amino acids
Structural information
PFAMPF01791
Orthologs
M. tuberculosis H37RvRv0478
M. lepromatosis Mx1-22AMLPM_2451
Cross-references
UniProtQ9CB45
Gene OntologyCytoplasm, Deoxyribonucleotide catabolic process, Deoxyribose-phosphate aldolase activity, Carbohydrate catabolic process
Enzyme Classification4.1.2.4
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE DEOXYRIBOSE-PHOSPHATE ALDOLASE DEOC (PHOSPHODEOXYRIBOALDOLASE) (DEOXYRIBOALDOLASE)
CommentsML2451c, len: 226 aa. Probable deoC, deoxyribose-phosphate aldolase (EC 4.1.2.4). Similar to Mycobacterium tuberculosis deoxyribose-phosphate aldolase Rv0478 SW:DEOC_MYCTU (Q11138) fasta scores: E(): 0, 78.6% identity in 224 aa, and to Bacillus subtilis deoxyribose-phosphate aldolase DeoC SW:DEOC_BACSU (P39121) fasta scores: E(): 9.9e-24, 44.7% identity in 206 aa. Contains Pfam match to entry PF01791 DeoC, Deoxyribose-phosphate aldolase.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS29265642927244-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2451c|deoC
VQGQPTRKQLAALVDHTLLKSEATHADVAALVAEAVELGVYAVCVSPSMVPAAVEAGAGGLRVATVVGFPSGEHVSIVKAQEAVQAVASGATEIDMVIAVGAALAGDLDAVRSDIEMVRSAIAGVVLKVIVESAVLLGQANERTLAEVCHVAEAAGADFVKTSTGFHPAGGASVRAVTLMTEAVGGRLGVKASGGIRTAVDAIALLDAGATRLGLSSTREVLDGLS
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