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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY TETR-FAMILY)
CommentsML2457, len: 233 aa. Probable regulatory protein, possibly tetR family. Similar to several putative trancriptional regulators e.g. Mycobacterium tuberculosis putative regulatory protein Rv0472c TR:O53757 (EMBL:AL021933) fasta scores: E(): 0, 88.8% identity in 232 aa. Contains a helix-turn-helix motif situated between residues 45..66 (+3.77 SD). Contains Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family.
Functional categoryRegulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS29301862930887+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML2457|ML2457
VAEHIPAVAVKTDGRKRRWHQHKVERRNELVDGTIDAIRRQGRFLSMDEIAGKIGVSKTVLYRYFIDKNDLTTAVMMRFAQTTLIPNMAAALSTNLDGFDLTREIIRVYVKTVAAEPEPYQFVMANSSASKSKVIADSERIIARMLAVMIRRRMQEAGMDAGGVEPWAYLIVGGVQLATHSWMSDPRMSADELIDYLTMLSWNALCGIVEVGGSLEKFRKQPHPSPIIPPRGP
      
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