Gene ML2461c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namefadB2
Gene length864 bp
IdentifierML2461c
Location 2934094 bp
Protein summary information
Molecular mass30533.2 Da
Isoelectric point5.04
Protein length288 amino acids
Structural information
PFAMPF00725, PF02737
Orthologs
M. tuberculosis H37RvRv0468
M. lepromatosis Mx1-22AMLPM_2461
Cross-references
UniProtQ9CB39
Gene OntologyFatty acid metabolic process, Oxidation-reduction process, Oxidoreductase activity, Coenzyme binding
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE 3-HYDROXYBUTYRYL-CoA DEHYDROGENASE FADB2 (BETA-HYDROXYBUTYRYL-CoA DEHYDROGENASE) (BHBD)
CommentsML2461c, len: 287 aa. Probable fadB2, 3-hydroxyacyl-CoA dehydrogenas (EC 1.1.1.157). Similar to Mycobacterium tuberculosis putative 3-hydroxyacyl-CoA dehydrogenase Rv0468 TR:O53753 (EMBL:AL021933) fasta scores: E(): 0, 89.5% identity in 287 aa, and to Clostridium acetobutylicum 3-hydroxybutyryl-CoA dehydrogenase SW:HBD_CLOAB (P52041) fasta scores: E(): 0, 43.3% identity in 282 aa. Contains Pfam match to entry PF00725 3HCDH, 3-hydroxyacyl-CoA dehydrogenase.
Functional categoryLipid metabolism
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS29340942934957-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2461c|fadB2
VSDAAIQRVGVVGAGQMGSGIAEVAVRAGVGVTVFETTDTLVTAGRNRIVKSLERGVSAGKVTERERDSALGHLVFTTDLNDLADRQLVIEAIVEDEAVKTKVFAELDRVITDPDAVLASNTSSIPIMKIAAATKNPQRVLGLHFFNPVPVLPLVELVSTLVTDEAAATRAEEFASGVLGKQVVRCSDRSGFVVNALLVPYLLSAIRIVEAGFATVEDVDKAVLAGLSHPMGPLRLSDLVGLDTLKLIADKMFEEFKEPHYGPPPLLLRMVEAGLLGKKSGQGFYTY
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