Gene ML2474 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML2474
Gene length516 bp
IdentifierML2474
Location 2948774 bp
Protein summary information
Molecular mass17973.5 Da
Isoelectric point8.99
Protein length172 amino acids
Structural information
PFAMPF00383
Orthologs
M. tuberculosis H37RvRv3752c
M. lepromatosis Mx1-22AMLPM_2474
Cross-references
UniProtQ9CB32
Gene OntologyZinc ion binding, Hydrolase activity
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
Productpossible cytidine/deoxycytidylate deaminase
CommentsML2474, len: 171 aa. Possible cytidine/deoxycytidylate deaminase (EC 3.5.4.-). Similar to several including: Mycobacterium tuberculosis probable cytidine/deoxycytidylate deaminase Rv3752c TR:O69719 (EMBL:AL022121) fasta scores: E(): 0, 87.4% identity in 151 aa, and to Neisseria meningitidis putative cytosine deaminase TR:CAB84390 (EMBL:AL162755) fasta scores: E(): 2e-19, 42.9% identity in 147 aa. Contains Pfam match to entry PF00383 dCMP_cyt_deam, Cytidine and deoxycytidylate deaminase zinc-binding region. Contains PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS29487742949289+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2474|ML2474
MPSAAGRRHQTRSVTTDEDLIRAALTVATTAGSRDVPIGAVVLGADGNELARAVNAREAIGDPTAHAEILAMRAAAGTLGNGWRLEGTTLAVTVEPCTMCAGALVLARIERLVFGAWQPKTGAVGSLWDVVRDHRLNHRPAVRGGVLAQECTAPLEAFFAHQRLSKGPPVR
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