Gene ML2487c
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE OROTATE PHOSPHORIBOSYLTRANSFERASE PYRE (OPRT) (OPRTASE) |
| Comments | ML2487c, len: 179 aa. Probable pyrE, purine/pyrimidine phosphoribosyltransferase (EC 2.4.2.10). Similar to Mycobacterium tuberculosis purine/pyrimidine phosphoribosyltransferase Rv0382c or MTV036.17c TR:O53717 (EMBL:AL021931) fasta scores: E(): 0, 86.2% identity in 174 aa, and to Pyrococcus abyssi orotate phosphoribosyltransferase pyre or pab2430 SW:PYRE_PYRAB (P56814) fasta scores: E(): 7.6e-16, 37.1% identity in 175 aa. Contains Pfam match to entry PF00156 Pribosyltran, Phosphoribosyl transferase domain. Contains PS00589 PTS HPR component serine phosphorylation site signature. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2961008 | 2961547 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML2487c|pyrE
VAELDRKELADLVRRLSVVQGCVTLSSGKQADHYVDLRRATLHHRASALIGRLMRELTKDWNYTVVGGLTLGADPVAIAIIHSPGRPIDAFVVRKYAKTHGLQRLIEGSEVSGQRVLVVEDTSTTGASALTAVRAVQDAGGDVVGVATVVDRGTGAAEAIKAEGLLYRSVLGLADLGLG
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