Gene ML2493c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namehspR
Gene length399 bp
IdentifierML2493c
Location 2969306 bp
Protein summary information
Molecular mass14982.2 Da
Isoelectric point11.54
Protein length133 amino acids
Structural information
PFAMPF00376
Orthologs
M. tuberculosis H37RvRv0353
M. lepromatosis Mx1-22AMLPM_2493
Cross-references
UniProtQ9CB24
Gene OntologyRegulation of transcription, dna-dependent, Response to stress, Sequence-specific dna binding transcription factor activity, Nucleotide binding
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE HEAT SHOCK PROTEIN TRANSCRIPTIONAL REPRESSOR HSPR (MERR FAMILY)
CommentsML2493c, len: 132 aa. Probable hspR, heat shock transcriptional repressor. Similar to Mycobacterium tuberculosis HspR OR Rv0353 TR:O06302 (EMBL:Z95324) fasta scores: E(): 0, 80.0% identity in 125 aa, and to Streptomyces albus TR:P96458 (EMBL:U43299) fasta scores: E(): 3.9e-20, 50.0% identity in 152 aa. Contains Pfam match to entry PF00376 merR, Bacterial regulatory proteins, merR family.
Functional categoryVirulence, detoxification, adaptation
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS29693062969704-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2493c|hspR
VMTRNSRDPRQQESRTFLISAAAELAGMHAQTLRTYDRLGLVSPSRASGGGRRYSQHDVELLRQVQRLSQNEGVNLAGIKRIIELTNQVEALQLKLQELTDELVMLRANQRRDLAVVPKSTALVLWQPRKPR
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