Gene ML2494c (dnaJ) in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namednaJ1
Gene length1167 bp
IdentifierML2494c
Location 2969708 bp
Protein summary information
Molecular mass41307.1 Da
Isoelectric point8.57
Protein length389 amino acids
Structural information
PFAMPF00226, PF00684, PF01556
Orthologs
M. tuberculosis H37RvRv0352
M. lepromatosis Mx1-22AMLPM_2494
Cross-references
UniProtQ02605
Gene OntologyDna replication, Cytoplasm, Heat shock protein binding, Protein folding, Response to heat, Unfolded protein binding, Zinc ion binding, Atp binding
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE CHAPERONE PROTEIN DNAJ1
CommentsML2494c, len: 388 aa. Probable dnaJ1, chaperone protein. Similar to Mycobacterium tuberculosis DnaJ protein Rv0352 SW:DNAJ_MYCTU (P07881; O08380) fasta scores: E(): 0, 91.8% identity in 391 aa. Also similar to ML0625 from M. leprae. Contains Pfam match to entry PF01556 DnaJ_C, DnaJ C terminal region. Contains Pfam match to entry PF00684 DnaJ_CXXCXGXG, DnaJ central domain (4 repeats). Contains Pfam match to entry PF00226 DnaJ, DnaJ domain. Contains PS00636 Nt-dnaJ domain signature. Contains PS00637 CXXCXGXG dnaJ domain signature. Note previously known as dnaJ.
Functional categoryVirulence, detoxification, adaptation
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS29697082970874-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2494c|dnaJ1
MAQREWVEKDFYKELGVSSDASPEEIKRAYRKLARYLHPDANPDNSAGERFKVVSEAHNVLSDPVKRKEYDETRRLFAGGWLGGRRFDSSFGDFGMGGDGAEFNLNDLFDAASRTGGTNIGDLFGGLFGRGASVRPSRPRRGNDLETEADLDFVEAAKGVAMPLRLTSPAPCTNCHGSGARPGISPKVCSTCNGSGVINRNQGAFGFSEPCTECRGSGSIIEHPCEECKGTGVTTRTRTINVRIPSGVEDGQRIRLAGQGEAGLRGAPSGDLYVTVHVRPDKIFGRNGDDLTVTIPVSFTELALGSTLSVPTLDGTVGVRVPKGTSDGRILRVRGRGVPKRSGGHGDLLVTVKVAVPLNLEGAAQKALEAYAAAERSSGFNPRAGWGR
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