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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE GRPE PROTEIN (HSP-70 COFACTOR)
CommentsML2495c, len: 229 aa. Probable grpE protein (Hsp70 cofactor). Similar to Mycobacterium tuberculosis GrpE protein Rv0351 SW:GRPE_MYCTU (P32724; O08379) fasta scores: E(): 0, 68.6% identity in 229 aa, and to Streptomyces coelicolor GrpE protein SW:GRPE_STRCO (Q05562) fasta scores: E(): 3.5e-18, 36.8% identity in 212 aa. Contains Pfam match to entry PF01025 GrpE, GrpE. Contains PS01071 grpE protein signature.
Functional categoryVirulence, detoxification, adaptation
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS29708882971577-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML2495c|grpE
VTEGNPHEQVTVTDKRRIDPDTGEVRSIPLGDTPGGSEPAGMTDRSANSTDTMVDKVAELTSDLQRVQADFANYRKRALRDQQTASDRAKATVISQLLGVLDDFDRAREHGDLDSGPLKSVADKLMSALTGLGLVAFGVEGEDFDPVLHEAVQHEGDGGEGSKPVIGDVLRHGYKLGDQVLRHALVGVVDTIAGDGAETVAIVAPVDSTAKTEQGELGDNVTPHKEDGD
      
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