Gene ML2501 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML2501
Gene length2643 bp
IdentifierML2501
Location 2980189 bp
Protein summary information
Molecular mass96186.9 Da
Isoelectric point6.74
Protein length881 amino acids
Structural information
PFAMPF02754
Orthologues
M. tuberculosisRv0338c
Cross-references
UniProtQ9CB20
Gene OntologyIron-sulfur cluster binding, Oxidoreductase activity, Electron carrier activity
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE IRON-SULFUR-BINDING REDUCTASE
CommentsML2501, len: 880 aa. Probable iron-sulphur-binding reductase. Similar to Mycobacterium tuberculosis hypothetical protein Rv0338c TR:O33268 (EMBL:Z97991) fasta scores: E(): 0, 78.1% identity in 894 aa, and to Streptomyces coelicolor putative iron-sulphur-binding reductase SCH35.51C TR:Q9X8V5 (EMBL:AL078610) fasta scores: E(): 0, 48.2% id in 776 aa. Contains multiple possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF00037 fer4, 4Fe-4S binding domain. Contains PS00070 Aldehyde dehydrogenases cysteine active site. Contains 2 x PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS29801892982831+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2501|ML2501
VTTQMLIRMVLGLSMTAVVLLFAARRVLWLYKLTMSGQPANGRTDELGTRIWTQITEVFGQRRLLQWSLPGLTHLFTMWGFFILLTVYIEAYGVLFQPNFHLPIIGRWNAIGFLQDFFALAVLTSTVTFAIIRMRNEPKEYGRKSRFYGSHTGGAWLILFMIFNVIWTYAVFRGASVDALGEAFPYNSGAFFSHAIAAVLYPLGQGANQIIETVALLLHIGVMLAFLLIVLHSKHLHIFLAPINVTFKRLPDGLGPLMPMESDGEPINFEDPSEDAVFGRGKIEDFTWKAMLDFATCTECGRCQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGEKTAEKLEGLNLETTKDKSRHVPESGFGRVPGHGPEQATRPLVGTAEQGGVIDPDVLWSCVTCGACVEQCPVDIEHIDHIIDMRRYQVMMESEFPSELSTLFKNLETKGNPWGQNAGDRTNWIDEVDFDVPVYGEDVDSFDGYEYLFWVGCAGAYDDKAKKTTKAVAELLAIAGVKYLVLGTGETCNGDSAHRSGNEFLFQQLAAQAVEILDGLFEGVNSVDRKIVVTCPHCFNTIGKEYRQLGGNYTVLHHTQLLNWLVHDKKLVPVTPVSQDITYHDPCYLGRHNKVYEAPRELVRAAGANFTEMPRHAERSFCCGAGGARMWMEEHIGKRINHERVDEALATNATTIATACPFCRVMVTDGVNDRQEEAGRSGVEVLDVAQVLLGSLDYDKAKLPAKGTAAAEITKTAGLSPAKPTESEAPAPEKSTQAAASAAPAKGIRLAAGAKQPDAKKPVSQTTSAKATEAPAATVPVKGLGIAGGAKRPGAKKSPDQAETPAPTESKSEAKPEPSDHADGNPAPPTAPVKRLGITRSARPPGKH
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