Gene ML2528c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namemycP3
Gene length1428 bp
IdentifierML2528c
Location 3010280 bp
Protein summary information
Molecular mass48626.2 Da
Isoelectric point7.86
Protein length476 amino acids
Structural information
PFAMPF00082
Orthologs
M. tuberculosis H37RvRv0291
M. lepromatosis Mx1-22AMLPM_2528
Cross-references
UniProtQ9CD36
Gene OntologySerine-type endopeptidase activity, Proteolysis
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3)
CommentsML2528c, len: 475 aa. Probable mycP3, membrane-anchored mycosin (EC 3.4.21.-). Similar to many proposed proteases e.g. Mycobacterium tuberculosis putative protease Rv0291 TR:O53695 (EMBL:AL021930) fasta scores: E(): 0, 69.9% id in 468 aa. Also similar to ML0041 and ML1538 from M. leprae. Contains 2 Pfam matches to entry PF00082 Peptidase_S8, Subtilase family. Contains PS00137 Serine proteases.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS30102803011707-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2528c|mycP3
MMRSELRIGLAGIATTLVVFQATLLRGCPWALAISPPVVDPGVPPPNGAPGPVQIMQQRGSCITSGVIPGTDLGIVTSSQSMLNLPAAWQFSRGEGQLVAIVDTGVRPGPRLPNVEAGGDYVESSDGLTDCDGHGTLVAGIVAGQPAPSGEDGFSGVAPAARLLSIRVTSAKFSLRSLGGDPQLKQASLEVTRLSRAIVHAADLGARVINISAITCLPADRSIDQSGLGAAIRYAAVDKDALLVAPAGNAGSTGTVGGNMNCESNPLTDLGRPDDPRNWASVTSVSIPSWWQPYVLSVASLTPSGRPSKFTMAGPWVGIAAPGENIVSVSNRDSGDLANALPNDRDQQIALNGTSYAAGYVSGVAALVRSKYPELTAKQVMRRITATAHTGARTLSNVVGSGTLDSVAALTWDLPATNDSPPVPVKLVTVPPPPAPKDNTPRNVAFAGTATLVMVVAAVVGTATIAARRREGTTP
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