Gene ML2529c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameeccD3
Gene length1458 bp
IdentifierML2529c
Location 3011718 bp
Protein summary information
Molecular mass49866.0 Da
Isoelectric point8.05
Protein length486 amino acids
Structural information
PFAMPF04600
Orthologues
M. tuberculosisRv0290
Cross-references
UniProtQ9CD35
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductESX CONSERVED COMPONENT ECCD3. PROBABLE TRANSMEMBRANE PROTEIN.
CommentsML2529c, len: 485 aa. esx conserved component, probable transmembrane protein. Similar to Mycobacterium tuberculosis hypothetical protein Rv0290 TR:O86362 (EMBL:AL021930) fasta scores: 76.4% identity in 471 aa, and to Streptomyces coelicolor putative integral membrane protein SC3C3.21 TR:O86654 (EMBL:AL031231) fasta scores: E(): 1.9e-05, 23.8% identity in 483 aa. Contains multiple possible membrane spanning hydrophobic domains towards the C-terminus.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS30117183013175-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2529c|eccD3
MVYVFAEEFCEGPVTSGAVMPIVRVAILADSRLIEMALPTELPLREILPAVKRLVVPAASDNDSPLAANASLHLSLAPIGGAPFSLDASLDTVGVVDGDLLALQPVPVGPAAPGIVEDIADAAMIFSTARLQSWGPTHIRRGALAATTAVTFAATGLGVTYRAVTGALTGLLVVIVIAVLIALGGLVLRSRAARTGLVLSIAALVPIGAVFALAVPGIFGPAQVLLASAGVTAWSLIALIVPGPERVRIVAFFTATVVIGVAVMLEAGAALLWQLTPLTIGCGLILAALLVTVEAAQLSALWARFPLPVIPAPGDPTPSAPSFQVLEDLPRRVRISSAHQSGFIAAATLLSMLGSVAIALRPEAVSSVGWYLVAATAVAATLRARVWDSVACKAWLLAQPYLVASVLLGLYTATGRYVAASAALLVLVVVVLAWAVVALNPRIASSDSYSLPLRRLLGMVASGLDASLIPAMAYLVSLFSWVLNR
Bibliography