Gene ML2536c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameeccB3
Gene length1659 bp
IdentifierML2536c
Location 3020440 bp
Protein summary information
Molecular mass57974.8 Da
Isoelectric point7.38
Protein length553 amino acids
Structural information
PFAMPF05108
Orthologs
M. tuberculosis H37RvRv0283
M. lepromatosis Mx1-22AMLPM_2536
Cross-references
UniProtQ9CD29
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductESX CONSERVED COMPONENT ECCB3. POSSIBLE MEMBRANE PROTEIN.
CommentsML2536c, len: 552 aa. esx conserved component, possible membrane protein. Similar to several Mycobacterium tuberculosis hypothetical proteins e.g. Rv0283 TR:O53688 (EMBL:AL021930) fasta scores: E(): 0, 70.8% identity in 552 aa. Also similar to ML1544 from M. leprae. Contains a possible membrane spanning hydrophobic domain.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS30204403022098-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2536c|eccB3
MTSNELPGEWSGERRSFFSRTPVNDNPDKVVYRRGFVTRHQVTGWRFVMRRIASGIALHDTRMLVDPLRTQSRSVLVGALLVITGLIGCFVFSFIRPNGAAGNNAVLADRSTAALYVRVGDELHPVLNLTSARLIVGRSVNPITVKSSELDRFPRGNLIGIPGAPERMVQNTTHDANWTVCDVVSGEGGHAAHSMGVTVIAGPPDSHGMRAAVLGSAHGVLVDAPSERGGSTWLLWDGKRSEIDLADHAVTDALGFGVGFAEVPAPRPIGAGLFNAIPEAPPLKAPVIPNAGATPSFGVRAPIGAVVVSFGLAALGKNPYDSVRYYAVLPDGLQPISPVLAAILRNINSYGLQQPPRLGADEVDKLPVSRMLDTERYPEQQISLIDAGYAPVSCAYWSKPAGAATSFLSLMSGAALPVPDAARAVELVSAPSRGDSSTASRVVLTPGTGYFAQTVGVGSAAPATASLFWVSDTGVRYGIDTEADARSEATAGPGKIVEALGLKLPAVPIPWSILSLFAVGPTLSRADALLEHDGLAPDTRAGRTTTAYGEHR
Bibliography