Gene ML2537c
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | ESX CONSERVED COMPONENT ECCA3 |
| Comments | ML2537c, len: 640 aa. esx conserved component, similar to many Mycobacterium tuberculosis hypothetical proteins e.g. Rv0282 |Y282_MYCTU (O53687) fasta scores: E(): 0, 83.6% identity in 628 aa. The C-terminus is also similar to many CBXX/CFQX family proteins e.g. Alcaligenes eutrophus CBXP_ALCEU (Q04540) fasta scores: E(): 3.8e-24, 36.4% identity in 283 aa. Also similar to ML0055 and ML1536 from M. leprae. Contains Pfam match to entry PF00004 AAA, ATPases associated with various cellular activities (AAA). Contains PS00017 ATP/GTP-binding site motif A (P-loop). |
| Functional category | Cell wall and cell processes |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3022091 | 3024013 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML2537c|eccA3
MLISGRSGWAILGTGGKAAVNRGDAGKLGGQSVIARAHVKVDGDVVSRFATCCRALGLAVYDRQRPADLAAARSGFTALARIAHDQCDVWIGLAAAGDVSTPVLAAISCTADTAGMLQRQVELAPAALGFHYDTGLYLQFRAIGPDDFHLAYAASLASTGGPGPYAEADQIVTGIIDRRPGWRDARWVAAVIHYRAGRWSDVVKLLTPIVNDPDIDEAYTHAAKIALGTALARLGMFAPALSYLEEPAGPVAVAAVDGALAKALVLRAHTDEESASEVLQDLYAAHPDNEQIEQALSDTSFGIVTTTAARIDARTDPWDPETEPGVEDFIDPAAHERKAVLLHEAERQLAEFIGLDEVKNQVSRLKSSVAMELVRKQRGLMVAQRAHHLVFAGPPGTGKTTIARVVAKVYCGLGLLKKENIREVHRADLIGQHIGETEAKTNAVIDSALDGVLFLDEAYALVATGAKNDFGLVAIDTLLARMENDRDRLVVIIAGYRADLDKFLDTNEGLRSRFTRNIDFPSYASHELVEIAHKMAEQRDSVFEQAALDELEVLFANLATSSTPDSNGISRRSLDIAGNGRFVRNIVERSEEEREFRLDHSNNVGTGELSDEELMTVTSEDVRRSVEPLLRGLGLMVPHD
Bibliography
- [2009]. Systematic genetic nomenclature for type VII secretion systems. Nomenclature Product
