Gene ML2546c
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) |
| Comments | ML2546c, len: 548 aa. Probable fadD2, acyl-CoA ligase (EC 6.2.1.-). Similar to Rhizobium trifolii malonyl CoA synthetase MATB TR:Q9ZIP5 (EMBL:AF117694) fasta scores: E(): 2.4e-31, 31.2% identity in 507 aa and Mycobacterium tuberculosis hypothetical 59.9 kda protein Rv0270 TR:P95227 (EMBL:Z86089) fasta scores: E(): 0, 82.3% id in 558 aa. Contains Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme. Contains PS00455 Putative AMP-binding domain signature. |
| Functional category | Lipid metabolism |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3033668 | 3035314 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML2546c|fadD2
VTKLRHYLERGAAEVHYLRSIFESGALGFEPPLTYAAMAVAMRKWGDLAMLPAMPARRSPHRAALIDEEGTLTYKELDRAAHALANGLIAKGVRGGDGIAILARNHRWFVIANYGCARVGARIILLNSEFSGPQIKEVSEREGAKVIIYDDEYTKVVSKAEPALGKLRALGVNPDEEEPPGSTDETLAELIARSSSAPAPKVRKRASIIILTSGTTGTPKGANRNTPASLAPLGGILSKVPFRAHEVTLLPAPMFHALGYLHATLAMFLGSTLVLRRRFKPATVLEDIEKHQATAMVVVPVMLSRILDTLENLETKSDLSSLRVVFVSGSQLGAELATRALEELGPVIYNMYGSTEIAFATIAGPKDLQINSATVGPVVKGVKVKILDDSGKEVPRGQVGRIFVGNAFPFEGYTGGGGKQIIDGLLSSGDVGYFDEHDLLYISGRDDEMIVSGGENVFPAEVEDLISGHPEVVEATAIGVDDKEWGARLRAFVVKKQDATIDEDAIKAYVRDHLARYKVPREVIFLEELPRNPTGKVLKRELRDFEVH
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