Gene ML2564c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namefadA2
Gene length1374 bp
IdentifierML2564c
Location 3057494 bp
Protein summary information
Molecular mass48436.9 Da
Isoelectric point6.94
Protein length458 amino acids
Structural information
PFAMPF00108, PF02803
Orthologues
M. tuberculosisRv0243
Cross-references
UniProtO69505
Gene OntologyTransferase activity, Metabolic process
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE ACETYL-CoA ACYLTRANSFERASE FADA2 (3-KETOACYL-CoA THIOLASE) (BETA-KETOTHIOLASE)
CommentsML2564c, len: 457 aa. Probable fadA2,acetyl-CoA acetyltransferase (EC ). Similar to many Prokaryotic and Eukaryotic thiolases including: Escherichia coli probable 3-ketoacyl-coa thiolase YFCY SW:YFCY_ECOLI (P76503) fasta scores: E(): 0, 36.9% identity in 434 aa and to Rattus norvegicus trifunctonal enzyme beta subunit, mitochondrial precursor SW:ECHB_RAT (Q60587) fasta scores: E(): 0, 37.2% identity in 462 aa. Contains Pfam match to entry PF00108 thiolase, Thiolase. Contains PS00099 Thiolases active site.
Functional categoryLipid metabolism
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS30574943058867-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2564c|fadA2
MLGETRRLQVAPASSVASDKTIQRTTFAKQRVAVLGGNRIPFARSNGAYAEASNQDMFSAALSGLVDRFGLAGERLDMVIGGAVLKHSRDFNLMRECVLGSQLSPYTPAFDLQQACATGLQAAIVAADGIAAGRYEVAVAGGVDTTSDVPISLGDNLRRNLLKLRRSKSNVQRLKLVGALPANIGVEIPANSEPRTGLSMGEHAAITAKKMGIKRVDQDELAAASHRNMASAYDRGFFDDLVTPFLGLYRDDNLRPNSHVEKLATLRPVFGVQAGDATMTAGNSTSLTDGASVALLATEQWVAAHSLTPFAYWVDAEIAAVDYVSGNDGLLMAPTYAVPRLLARNGLSFQDFDFYEIHEAFASVVLAHLQAWESEEYCRQCLGLDTALGPIDRSKLNVNGSSLAAGHPFAATGGRILVQTAKQLAEQKATQKGCGPMRALISVCAAGGQGVAVILEA
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