Gene ML2564c
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE ACETYL-CoA ACYLTRANSFERASE FADA2 (3-KETOACYL-CoA THIOLASE) (BETA-KETOTHIOLASE) |
| Comments | ML2564c, len: 457 aa. Probable fadA2,acetyl-CoA acetyltransferase (EC ). Similar to many Prokaryotic and Eukaryotic thiolases including: Escherichia coli probable 3-ketoacyl-coa thiolase YFCY SW:YFCY_ECOLI (P76503) fasta scores: E(): 0, 36.9% identity in 434 aa and to Rattus norvegicus trifunctonal enzyme beta subunit, mitochondrial precursor SW:ECHB_RAT (Q60587) fasta scores: E(): 0, 37.2% identity in 462 aa. Contains Pfam match to entry PF00108 thiolase, Thiolase. Contains PS00099 Thiolases active site. |
| Functional category | Lipid metabolism |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3057494 | 3058867 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML2564c|fadA2
MLGETRRLQVAPASSVASDKTIQRTTFAKQRVAVLGGNRIPFARSNGAYAEASNQDMFSAALSGLVDRFGLAGERLDMVIGGAVLKHSRDFNLMRECVLGSQLSPYTPAFDLQQACATGLQAAIVAADGIAAGRYEVAVAGGVDTTSDVPISLGDNLRRNLLKLRRSKSNVQRLKLVGALPANIGVEIPANSEPRTGLSMGEHAAITAKKMGIKRVDQDELAAASHRNMASAYDRGFFDDLVTPFLGLYRDDNLRPNSHVEKLATLRPVFGVQAGDATMTAGNSTSLTDGASVALLATEQWVAAHSLTPFAYWVDAEIAAVDYVSGNDGLLMAPTYAVPRLLARNGLSFQDFDFYEIHEAFASVVLAHLQAWESEEYCRQCLGLDTALGPIDRSKLNVNGSSLAAGHPFAATGGRILVQTAKQLAEQKATQKGCGPMRALISVCAAGGQGVAVILEA
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