Gene ML2565 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namefabG4
Gene length1365 bp
IdentifierML2565
Location 3058972 bp
Protein summary information
Molecular mass47325.7 Da
Isoelectric point6.17
Protein length455 amino acids
Structural information
PFAMPF00106
Orthologs
M. tuberculosis H37RvRv0242c
M. lepromatosis Mx1-22AMLPM_2565
Cross-references
UniProtO69504
Gene OntologyMetabolic process, Oxidoreductase activity, Binding
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE FABG4 (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE)
CommentsML2565, len: 454 aa. Probable fabG4, 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100). Highly similar to Mycobacterium tuberculosis fabG4, 3-oxoacyl-[acyl-carrier protein] reductase Rv0242c TR:O53665 (EMBL:AL021929) fasta scores: E(): 0, 84.8% id in 454 aa. The C-terminal portion of the predicted product of this CDS is similar to many 3-oxoacyl-[acyl-carrier protein] reductases e.g. Vibrio harveyi FabG SW:FABG_VIBHA (P55336) fasta scores: E(): 4.5e-27, 41.1% identity in 241 aa. Contains Pfam match to entry PF00678 adh_short_C2, Short chain dehydrogenase/reductase C-terminus. Contains Pfam match to entry PF00106 adh_short, short chain dehydrogenase. Contains PS00061 Short-chain dehydrogenases/reductases family signature.
Functional categoryLipid metabolism
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS30589723060336+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2565|fabG4
VAPKCSSDLFSQIVSSGPGSFVAKQLGVPRPETLRRYRPSDAPLCGSLLIGGDGRLVEPLRATLEKDYDLVSNNLGGRWTDSFGGLVFDATGITAPAELKGLHNFFTPLLRNLGRCARVVVIGTTPDATTSTDERIAQRALEGFSRSLGKELRRGATVALVYLSPDAKPAATGLESTMRFILSAKSAYVNGQVFYVGAADSTPPTNWDRPLENKVAIVTGAARGIGAAIAEVVARDGARVVAIDVESAAEALDETANRVGGTTLSLDVTADDAVDKITEHLHDYQGGHADILVNNAGITRDKLLANMDDCRWDAVLEVNLLAPQRLTEGLVGNGSISKGGRVIVLSSMAGIAGNRGQTNYATAKAGVIGLTQALAPGLAEKGITINAVAPGFIETQMTAAIPLATREVGRRLNSLLQGGLPVDVAETIAYFAIPASNAVTGNVIRVCGQAMLGA
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