Gene ML2580c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML2580c
Gene length1155 bp
IdentifierML2580c
Location 3080183 bp
Protein summary information
Molecular mass41886.6 Da
Isoelectric point11.25
Protein length385 amino acids
Structural information
PFAMPF01757
Orthologs
M. tuberculosis H37RvRv0228
M. lepromatosis Mx1-22AMLPM_2580
Cross-references
UniProtQ7APT8
Gene OntologyGO:0008415
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE INTEGRAL MEMBRANE ACYLTRANSFERASE
CommentsML2580c, len: 384 aa. Probable integral membrane acyltransferase (EC 2.3.1.-). Similar to Mycobacterium tuberculosis integral membrane acyltransferase Rv0228 TR:P96410 (EMBL:Z92669) fasta scores: E(): 0, 79.5% identity in 381 aa, and to Streptomyces mycarofaciens acyltransferase involved in midecamycin biosynthesis SW:MDMB_STRMY (Q00718) fasta scores: E(): 1.3e-13, 28.8% identity in 400 aa. Also similar to ML1101 from M. leprae.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS30801833081337-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2580c|ML2580c
VTDVQQVGGIRSFLPAVEGMRACAAIGVVVTHVAFQTGHSSGIVGRLFGRFDLAVAVFFALSGFLLWRGHAATARQPVPKDEQPHTSHYLRSRVVRIMPAYLVAVVVILSLLPGANHASWIVWLANLTLTQIYVPLTLTSGLTQMWSLSVEASFYLALPILALLTRRISVRARVPVIAAAVVISWAWGWVPVHTGSGVNPLTWPPAFFSWFAAGMLLAEWSYSRISLPHRLARSRLTMAVMTLLAYLVAVSPLAGPEGLVPGTATQFAVKMAMGSLVAFALVAPLVLDRPETLHRVLGSTGMVTLGRWSYGMFVWHLAALAMVFPVLGAFPFTGRMLMVLMLTLIFSFAIAAVSYALVESPCREALRRWECRRKPAVVPQLNTY
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