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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE INTEGRAL MEMBRANE ACYLTRANSFERASE
CommentsML2580c, len: 384 aa. Probable integral membrane acyltransferase (EC 2.3.1.-). Similar to Mycobacterium tuberculosis integral membrane acyltransferase Rv0228 TR:P96410 (EMBL:Z92669) fasta scores: E(): 0, 79.5% identity in 381 aa, and to Streptomyces mycarofaciens acyltransferase involved in midecamycin biosynthesis SW:MDMB_STRMY (Q00718) fasta scores: E(): 1.3e-13, 28.8% identity in 400 aa. Also similar to ML1101 from M. leprae.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS30801833081337-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML2580c|ML2580c
VTDVQQVGGIRSFLPAVEGMRACAAIGVVVTHVAFQTGHSSGIVGRLFGRFDLAVAVFFALSGFLLWRGHAATARQPVPKDEQPHTSHYLRSRVVRIMPAYLVAVVVILSLLPGANHASWIVWLANLTLTQIYVPLTLTSGLTQMWSLSVEASFYLALPILALLTRRISVRARVPVIAAAVVISWAWGWVPVHTGSGVNPLTWPPAFFSWFAAGMLLAEWSYSRISLPHRLARSRLTMAVMTLLAYLVAVSPLAGPEGLVPGTATQFAVKMAMGSLVAFALVAPLVLDRPETLHRVLGSTGMVTLGRWSYGMFVWHLAALAMVFPVLGAFPFTGRMLMVLMLTLIFSFAIAAVSYALVESPCREALRRWECRRKPAVVPQLNTY
      
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