Gene ML2587 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameyrbE1A
Gene length804 bp
IdentifierML2587
Location 3090774 bp
Protein summary information
Molecular mass27942.1 Da
Isoelectric point8.93
Protein length268 amino acids
Structural information
PFAMPF02405
Orthologs
M. tuberculosis H37RvRv0167
M. lepromatosis Mx1-22AMLPM_2587
Cross-references
UniProtQ9CD16
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductCONSERVED HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN YRBE1A
CommentsML2587, len: 267 aa. Probable yrbE1A, conserved hypothetical integral membrane protein. Highly similar to several Mycobacterium tuberculosis hypothetical proteins found within the four Mce loci, associated with virulence, e.g. Rv0167 TR:O07412 (EMBL:Z97050) fasta scores: E(): 0, 88.5% identity in 262 aa. Orthologue of M. tuberculosis YrbE1A (Rv0167). Contains possible membrane spanning hydrophobic domains.
Functional categoryVirulence, detoxification, adaptation
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS30907743091577+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2587|yrbE1A
VTTETRSSLVEYAHTKLQTPLVLVGGFFRMLVLTGKALFRRPFQWREFILQCWFIMRVAFLPTVMVSIPLTVLLIFTLNVLLAQFSAADLSGAGAAIGAVTQLGPLTTVLVVAGAGSTSICADLGARTIREEIDAMEVLGIDPIHRLVVPRVLAATLVATLLNGLVITVGLVGGYLFGVYLQNVSGGAYLATLTTITGLPEVVIATVKAATFGLIAGLVGCYRGLIVRGGSNGLGAAVNETVVLCVVALYAVNVVLTTIGVRFGTGH
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