Gene ML2589 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namemce1A
Gene length1326 bp
IdentifierML2589
Location 3092454 bp
Protein summary information
Molecular mass47149.4 Da
Isoelectric point7.14
Protein length442 amino acids
Structural information
PFAMPF02470
Orthologs
M. tuberculosis H37RvRv0169
M. lepromatosis Mx1-22AMLPM_2589
Cross-references
UniProtQ9CD14
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductMCE-FAMILY PROTEIN MCE1A
CommentsML2589, len: 441 aa. Probable mce1A, Mce-family protein. Highly similar to Mycobacterium tuberculosis Mce proteins associated with entry and survival inside macrophage e.g. Rv0169 ORMTCI28.08 TR:P72013 (EMBL:Z97050) fasta scores: E(): 0, 67.5% identity in 456 aa.Orthologue of M. tuberculosis Mce1A (Rv0169). Contains a possible N-terminal signal sequence.
Functional categoryVirulence, detoxification, adaptation
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS30924543093779+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2589|mce1A
MTSSTKINASRKPPYKLAGVGLLVVAVVIFGLVYGQFRGNFTPKSKLTMLADRAGLVMDRGSKITYNGVKIGRVADISETVRNGRPVAEFTLDVYPRYLSLIPANVNADIKATTVFGGKYVSLTTPEHPSQKRLTPQTVIDARSVTTEINTLFQTITLIAEKVDPIKLNLTLSAAAQSLAGLGERFGQSIVNGNSVLDDVNSQLPQARHDIQQLASLGDTYANSASDFFDFLNNSIVTSRTINQQQKDLDQVLLAAVGFGNTGADIFSRSGPYLARGAADLVPTAQLLDTYSPAIFCTLRNYHDIEPKVTSFLGGNGYSINDHVELLSGLGFLLNPTSAISIIGAGVLSQGLLAPLGLAGVVNGAANPYIYPENLPRVNARGGPGGAPGCWQHITRDLWPTPELVMDTGNSIAPYNHLDSGSPYAIEYVWGRQVGDNTINP
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