Gene ML2591 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namemce1C
Gene length1560 bp
IdentifierML2591
Location 3094813 bp
Protein summary information
Molecular mass54450.7 Da
Isoelectric point7.03
Protein length520 amino acids
Structural information
PFAMPF02470
Orthologs
M. tuberculosis H37RvRv0171
M. lepromatosis Mx1-22AMLPM_2591
Cross-references
UniProtQ9CD12
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductMCE-FAMILY PROTEIN MCE1C
CommentsML2591, len: 519 aa. mce1C, Mce-family protein. Highly similar to several Mycobacterium tuberculosis hypothetical proteins found within the four Mce loci, associated with virulence, e.g. Rv0171 TR:O07415 (EMBL:Z97050) fasta scores: E(): 0, 72.4% identity in 525 aa. Orthologue of M. tuberculosis Mce1C (Rv0171). Contains a possible N-terminal signal sequence.
Functional categoryVirulence, detoxification, adaptation
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS30948133096372+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2591|mce1C
MRTLELPNRLRSGLIGVLVVLLIIGVGQSFTSVPILFARPSYYGQFTDTGGLNKGDKVRIAGMDVGKVEALKIDGDHVVIKFSIGTNRIGTASRLGIRTDTVLGKKVLEVETRGTQLLRPGDSLPLGQSTTPYQSYDAFFDATKVASGWNIDTIKQSLKVVSETIDQTYPHLSAALDGVAKFSDTIGARDKEIKHLIAQANQVASVLGDRGAQVDRLLVNTKTLIAAFNERGRAVDALLGNVAAFAAQVQRLINDNPNLNHVLEQLHQLSGILVQHKDDLANTLIQVAAFLPSLNEAIGSGPFFKVVLHNLAPYQILQPWVDAAFKKRGIDPENFWRSAGLPEFRFPDPNGTRFPNGAPPPAPPVLEGTPENPGPAVPPGSPCSYTPAHPGGNNTIGDEMGLPRPWNPLPCAGATAGPYGGPAFPAPIDVQTSPPNPDGLPLLPGIAIAGRPGDPAPNVPGTPVPLPPNAPPGARTEQLAPAAPAQDSSAPHEPREQLSAPLINPGGTGGSGGAGGSRN
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