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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE MCE-FAMILY LIPOPROTEIN LPRK (MCE-FAMILY LIPOPROTEIN MCE1E)
CommentsML2593, len: 392 aa. Possible lprK, Mce-family lipoprotein. Highly similar to several Mycobacterium tuberculosis hypothetical proteins found within the four Mce loci, associated with virulence, e.g. Rv0173 TR:O07417 (EMBL:Z97050) fasta scores: E(): 0, 76.3% identity in 389 aa. Contains a possible N-terminal signal sequence and an appropriately positioned Prokaryotic membrane lipoprotein lipid attachment site. Orthologue of M. tuberculosis lprK (mce1E, Rv0173). Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS30979613099139+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML2593|lprK
VRRAMSVVHTSRVRHQTWRGLVMLVAALLLSSCGWRGISNVSIPGGPGSGKGAYTIYVQVPDTLAINGNSKVMVADVTVGSIRAINLKNWVATLTLGLNKDVQLPKNTTAKIGQTSLLGSQHVELAAPANPSLELLKNGDTIPLKNSSVFPTTEQTLASLSLILRGGGIPNLETLTNEVFNIFHGRADQIHAFLTKLDTFASQLNQQRDDITHAIDSTNRLLTYVGGRSDVLDQILTDIPPLIKHFADTKNLLINAVGSVGQLSQAVDQYLSEARGPLHTDLQALACPLRELGRGAPYFIGAMKLILTQPYDVDTVPKIMRGDYQNVSLTLDVTYSAMDNAVLTGTGLSGALRALEQSFGRDPETMIPDVRYTTNPNDAPGGPLVERADRRC
      
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