Gene ML2617c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namemmpL11
Gene length3042 bp
IdentifierML2617c
Location 3122785 bp
Protein summary information
Molecular mass109744.0 Da
Isoelectric point7.38
Protein length1014 amino acids
Orthologs
M. tuberculosis H37RvRv0202c
M. lepromatosis Mx1-22AMLPM_2617
Cross-references
UniProtO06079
Gene OntologyPlasma membrane, Integral to membrane
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL11
CommentsML2617c, len: 1013 aa. Probable mmpL11, conserved transmembrane transportprotein. Similar to Mycobacterium tuberculosis putative membrane protein Mmpl11 Rv0202c SW:MMLB_MYCTU (O53653) fasta scores: E(): 0, 72.8% identity in 1017 aa, and to Streptomyces coelicolor putative integral membrane protein SC3A4.16C TR:CAB89762 (EMBL:AL354616) fasta scores: E(): 0, 31.8% identity in 761 aa. Also similar to ML2620 from M. leprae. Contains a possible N-terminal signal sequence and multiple other possible membrane spanning hydrophobic domains.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS31227853125826-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2617c|mmpL11
MRLSSYLRRFRWLVFTGWLLALVPAIYLAMTQSGKLTGGGFEVAGSQSLLVHDQLQEQYPDQGAVSLALVAAPRSDASYQDMNDAVALLRRIVSEFPGVSEVPNPTQLPPRPDRPYGVSLRLDDRNSVTSDVAKQLRTKVGIKGDQAGRTANGKVRLYVIGQGALSAAVAANSKHDIAEAERWNLPIILIVLLAVFGSLAAAAVPLALGVCTVVVTMGLVDLVSMHTIMSVFVTSTVSMFGIALAVDYSLFILMRFREELRSGRQPQEAVDAAMATSGLAVVLSGMTVIASLTGIYLINTAALKSMATGAILAVAIAMLASITLTPAALATFGRAAVKRSVLMHWSQRSECTQSLFWTRWVGWVMHRPWISASAASTILIIMATPVTSMMLGNSLLRQFNSSHEIRAGVAAAAQALGPGALGPVQVLITFPDDPNTQASSPKHRQTIGAIRNRMLQAKNVMSVAPPQFADNNCSALLGAVLSVDPEDLGARETVDWMRTELPKVPGAAHVNVGGPTALINDFDDRVAKTEPLMLVFVALIAFVMLLISIRSVFLAFKGVLMTLLSVAAAYGSLVMVFQWGWLENLGFTHINSIDSTVPPLVLAMTFGLSMDYEIFLLTRIRERFLQTGHTRDAVAYGVSTSARTITSAALIMIAVFVGFAFAGMPLVAEIGVACAVAIAVDVTAVRLVLVPTLMAMFAQWNWWLPRWLSRALPAVDFDKPFPPVDLNEIVVLPADISATKVPCGDLRMVLKLAAKLKNLAPDAICVADPLAFTGCGRNNKRSDRVLPGAATQESEEDPAMGKASDSTAALTAAQVGPVTRTNGHWTARNLVIGLTHRNSITRVMPWSDRPVHPFTLWRSRFSVAIDALEAHIAVQADAPDQPNYQRCSPVETAHVQLPTGDRLLIPTGAETLRLVSYLIMCRNSIRDYAELADMVDAIEPETAAVVLTELDRYYSCQLPMRQWMATQLVRRLSDPHPVDLTEDQWSDPDNKAEWQDVRQRCLSVAVAMLEEAR
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