Gene ML2620c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namemmpL3
Gene length2868 bp
IdentifierML2620c
Location 3128842 bp
Protein summary information
Molecular mass102760.0 Da
Isoelectric point10.05
Protein length956 amino acids
Structural information
PFAMPF03176
Orthologs
M. tuberculosis H37RvRv0206c
M. lepromatosis Mx1-22AMLPM_2620
Cross-references
UniProtO06081
Gene OntologyPlasma membrane, Integral to membrane
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL3
CommentsML2620c, len: 955 aa. Possible mmpl3, conserved transmembrane transport protein. Similar to many Mycobacterium tuberculosis mmp-family membrane proteins e.g. Mmpl3 OR Rv0206c SW:MML3_MYCTU (O53657) fasta scores: E(): 0, 75.7% identity in 966 aa, and to Streptomyces coelicolor putative membrane transport protein SCF51A.01C TR:Q9RL63 (EMBL:AL121596) fasta scores: E(): 0, 28.8% identity in 791 aa. Also similar to ML2617 from M. leprae. Contains multiple possible membrane spanning hydrophobic domains.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS31288423131709-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2620c|mmpL3
VFAWWGRTVYRYRFIVIGITVALCLCGGVFGLSLGKHVTQSGFYDDSSQSVKASILGDQVYGRDRSGHIVAIFHAPDGKTVNDPAWAKKITDELNQFQRNNSNKVTGWAGYLRASDTTNTVVQGMATPDKKYTFVSIPLKGDDDDTILNNYKAIAPDLQKLDGGTVQLAGLDPIANALTSTIATDQRRMEVLALPLVAVVLFLVFGGVIAACLPVMVGGLSIAGALGILRFIALFGPVHFFAQPVVSLIGLGIAVDYGLFVVSRFREEIAEGYDTEAAVRRTVMTAGRTVTFSAVLIAASGASLLLLPQGFVKSLTYALIAAVTLAALLSITLLPACLAILAKHVDALGVRTLFRVPLLRNWRMSHACLNWLADRLQKTKTREEVEAGFWGKLVNFVMKRPLVFAIPIVIGMILLVIPLGNLSFGGMSEKYLPPNNAVRQSQEHFDQLFPGYRTNPLTLVIQTSNHQPVTDQEIADIRSKAMAISGFIEPDNNYVNMWQERTVAPGASKDPSVRVLQNGLINPNDASKKINELRSITPPKGLTVSVGGTPALEQDSIHSLVAQAPLMVIMLITTTMLLMFLAFGSFVLPIKAAVMSALTLGSTMGILTWIFVDGHLSKWLNFTPTPLMVVIIALVVAVGYGLATDYEVFLVSRMVEARAESMSTQEAVRIGTASTGRLITAAALVLAVVAGSFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVPSVMKLLGDDCWWAPRWARLLQNRIGLGEIHLPDERRRPTVSGRPVRPPVTAASLAAPASRVPRGPTHPATLEPSQRARSGLASRPQIKRPQELPSGASTARIQMRPSQSVEATTTRLSVPGNAPTTAAVSSSQGVQAVPLAATRHPLPTPSPASGQTRAMPVPANRSSDNASETAEPTTALPIMRPQDNDSEVATEKLNALGQGDNSRQHRRATGGGISAQDLLRREGRL
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